Effects of antimuscarinic drugs on the colon

  • Giorgio Cittadini


Tone, motility and secretion of the colon are under the control of the autonomic nervous system. Under the stimulation of the parasympathetic system, a marked increase in tone and motility is recorded, together with an increase in secretion and sphincter relaxation. Conversely, under the stimulation of the sympathetic system, tone and motility are slightly reduced, with secretion inhibition and sphincter contraction. Parasympathetic innervation becomes particularly important in DCBE, for the greater control it exerts on the above mentioned colon functions, which may significantly affect the results of the examination, and also because these effects can be easily inhibited with appropriate drugs.


Nicotinic Receptor Ammonium Compound Double Contrast Barium Enema Antimuscarinic Drug Parasympathetic Innervation 
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Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • Giorgio Cittadini
    • 1
  1. 1.Department of RadiologyUniversity of Genoa School of Medicine San Martino HospitalGenoaItaly

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