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Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E. pp 1105–1117Cite as

The neural and humoral response to acute neurological illness is the mechanism of consequent new organ failures

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Abstract

The neural and humoral response to acute neurological illness is important during the initial onset, and while critical for the body to successfully deal with acute physical stressors such as low blood pressure, hypoxia etc., may have a deleterious effect after the acute phase. For example, glucocorticoid excess adversely affects the nervous system, particularly the hippocampus [1]. These effects include disruption of synaptic plasticity, atrophy of dendrites (i.e., reducing connections between neurones), compromise of the ability of neurones to survive various coincident insults, which are common after traumatic brain injury (TBI) [2].

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Authors
  1. P. J. D. Andrews
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Editors and Affiliations

  1. Department of Perioperative Medicine, Intensive Care and Emergency, Trieste University School of Medicine, Trieste, Italy

    Antonino Gullo M.D. (Head) (Head)

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© 2003 Springer-Verlag Italia

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Andrews, P.J.D. (2003). The neural and humoral response to acute neurological illness is the mechanism of consequent new organ failures. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2215-7_39

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  • DOI: https://doi.org/10.1007/978-88-470-2215-7_39

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0194-7

  • Online ISBN: 978-88-470-2215-7

  • eBook Packages: Springer Book Archive

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