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Sepsis and Organ Dysfunction pp 51–57Cite as

Phagocytosis and Lung Injury

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Abstract

Phagocytosis of pathogens by macrophages and neutrophils is a key component of innate immunity, with internalization leading in most cases to killing of the pathogen. However, while phagocytosis is a crucial element of host defence, aspects of the phagocytic response can also be associated with host tissue damage. I will review our current understanding of the basic mechanisms of phagocytosis, and potential sources of deleterious effects on the host.

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Authors
  1. J. W. Booth
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Editor information

Editors and Affiliations

  1. Department of Surgery, S. Louis University, School of Medicine, Fishers Island, New York, USA

    A. E. Baue M.D. (Emeritus Professor) (Emeritus Professor)

  2. Department of Clinical Sciences, Section of Anaesthesia, Intensive Care and Pain Clinic, Trieste University Medical School, Trieste, Italy

    G. Berlot M.D.  & A. Gullo M.D.  & 

  3. Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium

    J.-L. Vincent M.D.

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© 2002 Springer-Verlag Italia, Milano

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Booth, J.W. (2002). Phagocytosis and Lung Injury. In: Baue, A.E., Berlot, G., Gullo, A., Vincent, JL. (eds) Sepsis and Organ Dysfunction. Springer, Milano. https://doi.org/10.1007/978-88-470-2213-3_3

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  • DOI: https://doi.org/10.1007/978-88-470-2213-3_3

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0178-7

  • Online ISBN: 978-88-470-2213-3

  • eBook Packages: Springer Book Archive

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