Effects of immunotherapeutic strategies on cerebrospinal fluid parameters in multiple sclerosis

  • K. J. B. Lamers
  • S. T. F. M. Frequin
  • O. R. Hommes


Therapeutic strategies in MS are generally based on treatment with anti-inflammatory, immunosuppressive or immunomodulatory agents. Most applied therapeutic agents in MS are: corticosteroids, cyclophosphamide, azathioprine, cyclosporine, interferon, total lymphoid irradiation, plasma exchange, monoclonal antibodies, copolymer-I and immunoglobulins. Modes of administration are: oral, intramuscular, intravenous or intrathecal; administration of drugs can be carried out by both a short course of high dose or a chronic low dose during an extended period.


Multiple Sclerosis Multiple Sclerosis Patient Immunotherapeutic Strategy Myelin Basic Protein Level Chronic Progressive 
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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • K. J. B. Lamers
    • 1
  • S. T. F. M. Frequin
    • 2
  • O. R. Hommes
    • 1
  1. 1.Institute of NeurologyUniversity Hospital NijmegenNijmegenThe Netherlands
  2. 2.St. Antonius HospitalInstitute of NeurologyNieuwegeinThe Netherlands

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