Cerebrospinal fluid virological analysis in multiple sclerosis

  • P. Ferrante
  • R. Mancuso


The detection of virus-specific antibodies, of antigens, and the more recent detection of viral nucleic acids in cerebrospinal fluid (CSF) are powerful tools for the diagnosis of the most common viral diseases affecting the CNS, such as acute and subacute encephalomyelitis and other neurological diseases caused by the replication of viruses in the CNS. However, these virological techniques, including those most recently developed, are not so efficient in cases involving the verification of whether a viral agent may be responsible for such a complex disease as multiple sclerosis (MS).


POLYM Erase Chain Reaction mUltiple Sclerosis mUltiple Sclerosis Patient POLYM Erase Chain Reaction Analysis Hemagglutination Inhibition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • P. Ferrante
    • 1
  • R. Mancuso
    • 1
  1. 1.Laboratory of BiologyDon C. Gnocchi Foundation IRCCSMilanItaly

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