Skip to main content
  • 167 Accesses

Abstract

Conventional management of acute postoperative pain with intermittent intramuscular administration of fixed doses of drugs usually fails to produce adequate analgesia for a variety of reasons (1-4):

  • Delay between patient’s request and need satisfaction by the nurse

  • Drug absorption rate from intramuscular depots

  • Opioids underprescription for fear of side-effects, mainly respiratory depression

  • Wide interpatient variability of analgesic need, related to marked differences of pharmacokinetic and pharmacodynamic factors

  • Subjectivity of pain experience that makes difficult the use of any assessment index

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Baubillier E, Bonnet F (1991) Analgésie contrôlée par le patient. Cah Anesthesiol 39(8): 551–555

    PubMed  CAS  Google Scholar 

  2. Riegler FX (1994) Update on perioperative pain management. Section III Regular and special features. Clin Orthop Rel Res 305:283–292

    Google Scholar 

  3. Scherpereel PH (1991) Analgésie contrôlée par le patient (ACP). Ann Fr Anesth Reanim 10:269–283

    Article  PubMed  CAS  Google Scholar 

  4. White PF (1988) Use of patient-controlled analgesia for management of acute pain. JAMA 259:243–247

    Article  PubMed  CAS  Google Scholar 

  5. Sechzer PH (1990) Patient controlled analgesia (PCA): a retrospective. Anesthesiology 72: 735–736

    Article  PubMed  CAS  Google Scholar 

  6. Bennett RL, Batenhorst RL, Bivins BA et al (1982) Patient-controlled analgesia. A new concept of postoperative pain relief. Ann Surg 195(6):700–705

    Article  PubMed  CAS  Google Scholar 

  7. Langlade A, Briard C, Bouguet D et al (1994) Analgésie contrôlée par le patient et douleurs postopératoires. Cah Anesthesiol 42(2): 183–189

    PubMed  CAS  Google Scholar 

  8. Levin A, Klein SL, Brolin RE et al (1992) Patient-controlled analgesia for morbidly obese patients: an effective modality if used correctly (correspondence). Anesthesiology 76:857–858

    Article  PubMed  CAS  Google Scholar 

  9. Owen H, Brose WG, Plummer JL et al (1990) Variables of patient-controlled analgesia. 3. Test of an infusion-demand system using alfentanyl. Anaesthesia 45:452–455

    Article  PubMed  CAS  Google Scholar 

  10. Pasetto A, Colò F, Pasqualucci A et al (1993) Control of post-operative pain by a PCA throwaway device. In: Atti APICE, pp 241–245

    Google Scholar 

  11. Savoia G (1990) Le basi razionali dell’analgesia controllata dal paziente (PCA). Minerva Anestesiol 56(7–8):349–352

    PubMed  CAS  Google Scholar 

  12. Wasylak TJ, Abbott FV, English MJM et al (1990) Reduction of post-operative morbidity following patient-controlled morphine. Can J Anaesth 37(7):726–731

    Article  PubMed  CAS  Google Scholar 

  13. Casali R, Di Benedetto M, Masci P et al (1990) Pompa PCAl Bard nell’immediato dolore post-operatorio. Minerva Anestesiol 56(10): 1131–1132

    PubMed  CAS  Google Scholar 

  14. Paoletti F, Boanelli A, Falconi S (1995) Ruolo dei presidi infusionali monouso nella terapia antalgica domicihare. In: Atti Le nuove frontiere dell’impegno anestesiologico: il sistema di emergenza, i trapianti e la terapia antalgica domiciliare. Udine, pp 179–184

    Google Scholar 

  15. Owen H, Plummer JL, Armstrong I et al (1989) Variables of patient-controlled analgesia. 1. Bolus size. Anaesthesia 44:7–10

    Article  PubMed  CAS  Google Scholar 

  16. Parker PK, Holtmann B, White PF (1991) Patients controlled analgesia. Does a concurrent opioid infusion improve pain management after surgery? JAMA 266:1947–1952

    Article  PubMed  CAS  Google Scholar 

  17. Owen H, Szekely SM, Plummer JL et al (1989) Variables of patient-controlled analgesia. 2. Concurrent infusion. Anaesthesia 44:11–13

    Article  PubMed  CAS  Google Scholar 

  18. Vercauteren MP, Coppejans HC, Ten Broecke PW et al (1995) Epidural sufentanil for postoperative patient controlled analgesia (PCA) with or without background infusion: a double-blind comparison. Anesth Analg 80:76–80

    PubMed  CAS  Google Scholar 

  19. Baubillier E, Leppert C, Delaunay L et al (1992) Analgésie contrôlée par le patient: effet de l’adjonction d’une perfusion continue de morphine. Ann Fr Anesth Reanim 11:479–483

    Article  PubMed  CAS  Google Scholar 

  20. Burns JW, Hodsmann NBA, McLintock TTC et al (1989) The influence of patients characteristics on the requirements for postoperative analgesia. Anaesthesia 44:2–6

    Article  PubMed  CAS  Google Scholar 

  21. Stone PA, Macintyre PE, Jarvis DA (1993) Norpethidine toxicity and patient controlled analgesia. Br J Anaesth 71:738–740

    Article  PubMed  CAS  Google Scholar 

  22. Rubin P, Yee JP, Murthy VS et al (1987) Ketorolac tromethamine analgesia: no postoperative respiratory depression and less constipations. Chn Pharm Ther 41:182 (abstr)

    Google Scholar 

  23. Brasseur L (1992) Analgésie auto-controlée par voie péridurale et méthodes classiques d’analgésie. Cah Anesthesiol 40(7):474–476

    PubMed  CAS  Google Scholar 

  24. Chrubasik J, Hans W, Schulte-Monting J (1988) Relative analgesie potency of epidural fentanyl, alfentanyl, and morphine in treatment of postoperative pain. Anesthesiology 68: 929–933

    Article  PubMed  CAS  Google Scholar 

  25. Sjostrom S, Hartvig D, Tamsen A (1988) Patient controlled analgesia with extradural morphine or pethidine. Br J Anaesth 60:358–366

    Article  PubMed  CAS  Google Scholar 

  26. Marlowe S, Engstrom R, White PF (1989) Epidural patient controlled analgesia (PCA): an alternative to continuous epidural infusions. Pain 37:97–101

    Article  PubMed  CAS  Google Scholar 

  27. Chrubasik J, Wiemers K (1985) Continuous plus on demand epidural infusion of morphine for postoperative pain relief by means of a small, externally worn infusion device. Anesthesiology 62:263–267

    Article  PubMed  CAS  Google Scholar 

  28. Gambling DR, Christopher JH, Johnathan B et al (1993) Patient controlled epidural analgesia in labour: varying bolus dose and lockout interval. Can J Anaesth 40(3):211–217

    Article  PubMed  CAS  Google Scholar 

  29. Gambling DR, Yu P, Cole C et al (1988) A comparative study of patient controlled epidural analgesia (PCEA) and continuous infusion epidural analgesia (CIEA) during labour. Can J Anaesth 35(3):249–254

    Article  PubMed  CAS  Google Scholar 

  30. Giangreco R, Rossetto B, Colucci V et al (1990) Inefficacia della PCA endovenosa nel controllo del dolore in travaglio di parto. Minerva Anestesiol 56(10): 1127–1128

    PubMed  CAS  Google Scholar 

  31. Morisot P, Boureau F (1991) Evaluation de la douleur obstétricale par questionnaire d’adjectifs. Comparison de deux modalités d’analgésie péridurale. Ann Fr Anesth Reanim 10:117–126

    Article  PubMed  CAS  Google Scholar 

  32. Murât I, Dubois MC, Esteve C et al (1991) Analgésie auto-controlée chez l’enfant. Cah Anesthesiol 39(3): 161–164

    PubMed  Google Scholar 

  33. Robinson SL, Fell D (1991) Nausea and vomiting with use of a patient controlled analgesia system. Anesthesia 46:580–582

    Article  CAS  Google Scholar 

  34. White PF (1987) Mishaps with patient-controlled analgesia. Anesthesiology 66:81–83

    Article  PubMed  CAS  Google Scholar 

  35. Sharma SK, Davies MW (1993) Patients-controlled analgesia with a mixture of morphine and droperidol. Br J Anaesthesiol 71:435–436

    Article  CAS  Google Scholar 

  36. Ball D, Holmes K, Ralph S (1992) Solving the problems with patient controlled analgesia. BMJ 304:1113

    Article  PubMed  CAS  Google Scholar 

  37. Gould TH, Crosby DL, Harmer M et al (1992) Policy for controlling pain after surgery: effect of sequential changes in management. BMJ 305:1187–1193

    Article  PubMed  CAS  Google Scholar 

  38. Grover ER, Heath ML (1992) Patient-controlled analgesia. A serious incident. Anaesthesia 47:402–404

    Article  PubMed  CAS  Google Scholar 

  39. McKanzie R (1988) Patient-controlled analgesia (PCA). Anesthesiology 69:1027

    Article  Google Scholar 

  40. Notcutt WG, Knowles P, Kaldas R (1992) Overdose of opioid from patient-controlled analgesia pumps. BMJ 69:95–97

    CAS  Google Scholar 

  41. Southern DA, Read MS (1994) Overdosage of opiate from patient controlled analgesia device. BMJ 309:1002

    Article  PubMed  CAS  Google Scholar 

  42. Thomas DW, Owen H (1988) Patient-controlled analgesia-the need for caution. Anaesthesia 43:770–772

    Article  PubMed  CAS  Google Scholar 

  43. Sozio CA, Lorenzelli L (1995) Controllo del dolore oncologico con PCA. In: Atti Le nuove frontiere dell’impegno anestesiologico: il sistema di emergenza, i trapianti e la terapia antalgica domiciliare (1995). Udine, pp 266–267

    Google Scholar 

  44. Howell PR, Gambling DR, Pavy T et al (1995) Patient controlled analgesia following caesarean section under general anaesthesia: a comparison of fentanyl with morphine. Can J Anaesth 42(l):41–45

    Article  PubMed  CAS  Google Scholar 

  45. Santangelo E, Savoia G, Scopa C et al (1991) Sicurezza della PCA nel paziente geriatrico. Minerva Anestesiol 57(10):1080–1081

    PubMed  CAS  Google Scholar 

  46. De Leon-Casasola OA, Parker BM, Lema MJ et al (1994) Epidural analgesia versus intravenous patient controlled analgesia: differences in the postoperative course of cancer patients. Reg Anesth 19:307–315

    PubMed  Google Scholar 

  47. Testa G, Bozomati V, Rossi A (1994) Impiego del ketorolac in patients controlled analgesia (PCA) nel dolore post-operatorio. Minerva Chir 49:347–362

    Google Scholar 

  48. Dahal JB, Daugaard JJ, Larsen HV et al (1987) Patient-controlled analgesia: a controlled trial. Acta Anaesth Scand 31:744–747

    Article  Google Scholar 

  49. Eisenach JC, Grice SC, Dewan DM (1988) Patient controlled analgesia following cesarean section: a comparison with epidural and intramuscular narcotics. Anesthesiology 68:444–448

    Article  PubMed  CAS  Google Scholar 

  50. Harrison DM, Sinatra R, Morgese L et al (1988) Epidural narcotic and patient-controlled analgesia for post-cesarean section pain relief. Anesthesiology 68:454–457

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer-Verlag Italia, Milano

About this chapter

Cite this chapter

Pasetto, A., Varutti, A.M., Bonfreschi, V., Colò, F. (1996). Patient Controlled Analgesia (PCA): Clinical Experience. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2203-4_70

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2203-4_70

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-3-540-75014-7

  • Online ISBN: 978-88-470-2203-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics