Patient Controlled Analgesia (PCA): Clinical Experience

  • A. Pasetto
  • A. M. Varutti
  • V. Bonfreschi
  • F. Colò


Conventional management of acute postoperative pain with intermittent intramuscular administration of fixed doses of drugs usually fails to produce adequate analgesia for a variety of reasons (1-4):
  • Delay between patient’s request and need satisfaction by the nurse

  • Drug absorption rate from intramuscular depots

  • Opioids underprescription for fear of side-effects, mainly respiratory depression

  • Wide interpatient variability of analgesic need, related to marked differences of pharmacokinetic and pharmacodynamic factors

  • Subjectivity of pain experience that makes difficult the use of any assessment index


Respiratory Depression Patient Control Analgesia Postoperative Pain Relief Acute Postoperative Pain Background Infusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • A. Pasetto
  • A. M. Varutti
  • V. Bonfreschi
  • F. Colò

There are no affiliations available

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