Abstract
Conventional management of acute postoperative pain with intermittent intramuscular administration of fixed doses of drugs usually fails to produce adequate analgesia for a variety of reasons (1-4):
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Delay between patient’s request and need satisfaction by the nurse
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Drug absorption rate from intramuscular depots
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Opioids underprescription for fear of side-effects, mainly respiratory depression
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Wide interpatient variability of analgesic need, related to marked differences of pharmacokinetic and pharmacodynamic factors
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Subjectivity of pain experience that makes difficult the use of any assessment index
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© 1996 Springer-Verlag Italia, Milano
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Pasetto, A., Varutti, A.M., Bonfreschi, V., Colò, F. (1996). Patient Controlled Analgesia (PCA): Clinical Experience. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2203-4_70
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DOI: https://doi.org/10.1007/978-88-470-2203-4_70
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