Pathophysiology and Monitoring of Cerebral Edema

  • F. Della Corte
  • O. Piazza
  • A. Clemente
  • M. A. Pennisi


After primary neurologic damage due to a traumatic, ischemic, hypoxic or metabolic event, a secondary lesion may arise, worsening it and becoming a vicious circle. Locally, the initial energetic breakdown or the tissue mechanical disruption set off a number of biochemical chain reactions leading to a derangement of molecular structures and liberating toxic mediators. Globally, these reactions are responsible for brain edema and disorders of microcirculation (1).


Cerebral Blood Flow Brain Edema Cerebral Edema Cerebral Perfusion Pressure Blood Flow Velocity 
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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • F. Della Corte
  • O. Piazza
  • A. Clemente
  • M. A. Pennisi

There are no affiliations available

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