Pathophysiology and Monitoring of Cerebral Edema
After primary neurologic damage due to a traumatic, ischemic, hypoxic or metabolic event, a secondary lesion may arise, worsening it and becoming a vicious circle. Locally, the initial energetic breakdown or the tissue mechanical disruption set off a number of biochemical chain reactions leading to a derangement of molecular structures and liberating toxic mediators. Globally, these reactions are responsible for brain edema and disorders of microcirculation (1).
KeywordsCerebral Blood Flow Brain Edema Cerebral Edema Cerebral Perfusion Pressure Blood Flow Velocity
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