Lactic Acidosis: Diagnosis and Treatment

  • J.-L. Vincent


Measurements of blood lactate levels can be very useful for detecting the presence of tissue underperfusion and for guiding therapy. Increased blood lactate levels usually reflect an imbalance between the oxygen demand and the oxygen supply to the cells, but other conditions may also be responsible. The present chapter first reviews the biochemistry of blood lactate, then reviews the clinical conditions associated with hyperlactatemia and finally discusses some therapeutic implications.


Septic Shock Blood Lactate Lactate Level Lactic Acidosis Blood Lactate Level 
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© Springer-Verlag Italia, Milano 1996

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  • J.-L. Vincent

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