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Carbon Monoxide Poisoning: Mechanism, Clinical Presentation and Management

  • Chapter
Handbook on Hyperbaric Medicine

Abstract

Carbon monoxide (CO) poisoning is actually the first cause of accidental poisoning in Europe [1] and North America [2]. Despite efforts in prevention and public and medical education, this intoxication remains frequent, severe, and too often overlooked; frequent because carbon monoxide accounts for nearly 5000–8000 poisonings a year in France, and this number is likely to increase, because devices able to produce CO are used more and more by the general public. Besides, the energy crisis has led people to decreased air ventilation in homes. Thus, these two factors join together to increase the risk of CO production; severe because carbon monoxide is responsible for hundreds of deaths annually in Europe. But death is only one risk of carbon monoxide poisoning, and another one of major importance is neurological sequelae; underdiagnosed and thus inadequately managed. In 1979 a French Poison Control Center study [3] showed that nearly 30 % of CO poisoning was overlooked or misdiagnosed during the first visit to the hospital or by the general practitioner.

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Authors and Affiliations

  1. Service d’Urgences Respiratoires, de Réanimation et Médecine Hyperbare, Centre AntiPoison, Hôpital A. Calmette, Centre Hospitalier Régional Universitaire, Bld du Professeur Leclercq, 59037, Lille Cedex, France

    D. Mathieu, F. Wattel, R. Nevière & M. Mathieu-Nolf

  2. Hyperbaric Department, Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, Washington, 98111, USA

    N. B. Hampson

  3. Section of Pulmonary and Critical Care Medicine, Virginia Mason Clinic, 1100 Ninth Avenue, Seattle, Washington, 98111, USA

    N. B. Hampson

  4. Department of Anaesthesiology, SUNY Health Science Center, Syracuse, NY, 13210, USA

    E. M. Camporesi (Professor and Chair, Professor of Physiology)

  5. National Toxicology Information Centre, “Clinica del Lavoro” Foundation Pavia Medical Centre, 27100, Pavia, Italy

    C. Gandini & C. Gandini

  6. 2nd Division of Cardiology, H. Niguarda Cà Granda, 20100, Milan, Italy

    M. Broccolino & S. Scarpini

  7. 1st Service of Anaesthesia and Reanimation, H. Niguarda Cà Granda, 20100, Milan, Italy

    A. Travaglia & C. Pirovano

  8. Milan Poison Centre, H. Niguarda, Cà Granda, 20100, Milan, Italy

    C. Pirovano

  9. Biochemical Lab, H. Niguarda Cà Granda, 20100, Milan, Italy

    S. Brenna

  10. Anaesthesia, Intensive and Hyperbaric Care Department, Galeazzi Orthopaedic Institute, Via Riccardo Galeazzi 4, 20161, Milan, Italy

    G. Oriani

  11. Child Neuropsychiatric Clinic, H. San Gerardo, 20052, Monza, Italy

    M. Michael, A. Peretti & D. Grioni

  12. Department of Neuroradiology, Scientific Institute San Raffaele, 20100, Milan, Italy

    E. Triulzi

  13. Department of Neuroradiology, H. Niguarda Cà Granda, 20100, Milan, Italy

    N. Colombo

Authors
  1. D. Mathieu
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  2. F. Wattel
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  3. R. Nevière
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  4. M. Mathieu-Nolf
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  5. N. B. Hampson
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  6. E. M. Camporesi
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  7. C. Gandini
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  8. M. Broccolino
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  9. S. Scarpini
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  10. A. Travaglia
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  11. C. Pirovano
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  12. S. Brenna
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  13. G. Oriani
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  14. C. Gandini
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  15. M. Michael
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  16. A. Peretti
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  17. D. Grioni
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  18. E. Triulzi
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  19. N. Colombo
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Editor information

Editors and Affiliations

  1. Anaesthesia, Intensive and Hyperbaric Care Department, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy

    G. Oriani

  2. Divers Alert Network Europe, Via Puglie 82, 64026, Roseto degli Abruzzi, Italy

    A. Marroni

  3. Service de Réanimation Mèdicale et de Médicine Hyperbare, Hôpital Albert Calmette, Blvd. du Prof. Leclercq, 59037, Lille Cedex, France

    F. Wattel

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Mathieu, D. et al. (1996). Carbon Monoxide Poisoning: Mechanism, Clinical Presentation and Management. In: Oriani, G., Marroni, A., Wattel, F. (eds) Handbook on Hyperbaric Medicine. Springer, Milano. https://doi.org/10.1007/978-88-470-2198-3_9

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  • DOI: https://doi.org/10.1007/978-88-470-2198-3_9

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