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Carbon Monoxide Poisoning: Mechanism, Clinical Presentation and Management

  • D. Mathieu
  • F. Wattel
  • R. Nevière
  • M. Mathieu-Nolf
  • N. B. Hampson
  • E. M. Camporesi
  • C. Gandini
  • M. Broccolino
  • S. Scarpini
  • A. Travaglia
  • C. Pirovano
  • S. Brenna
  • G. Oriani
  • C. Gandini
  • M. Michael
  • A. Peretti
  • D. Grioni
  • E. Triulzi
  • N. Colombo

Abstract

Carbon monoxide (CO) poisoning is actually the first cause of accidental poisoning in Europe [1] and North America [2]. Despite efforts in prevention and public and medical education, this intoxication remains frequent, severe, and too often overlooked; frequent because carbon monoxide accounts for nearly 5000–8000 poisonings a year in France, and this number is likely to increase, because devices able to produce CO are used more and more by the general public. Besides, the energy crisis has led people to decreased air ventilation in homes. Thus, these two factors join together to increase the risk of CO production; severe because carbon monoxide is responsible for hundreds of deaths annually in Europe. But death is only one risk of carbon monoxide poisoning, and another one of major importance is neurological sequelae; underdiagnosed and thus inadequately managed. In 1979 a French Poison Control Center study [3] showed that nearly 30 % of CO poisoning was overlooked or misdiagnosed during the first visit to the hospital or by the general practitioner.

Keywords

Carbon Monoxide Hyperbaric Oxygen Hyperbaric Oxygen Therapy Heart Damage COHb Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • D. Mathieu
    • 1
  • F. Wattel
    • 1
  • R. Nevière
    • 1
  • M. Mathieu-Nolf
    • 1
  • N. B. Hampson
    • 2
    • 3
  • E. M. Camporesi
    • 4
  • C. Gandini
    • 5
  • M. Broccolino
    • 6
  • S. Scarpini
    • 6
  • A. Travaglia
    • 7
  • C. Pirovano
    • 7
    • 8
  • S. Brenna
    • 9
  • G. Oriani
    • 10
  • C. Gandini
    • 5
  • M. Michael
    • 11
  • A. Peretti
    • 11
  • D. Grioni
    • 11
  • E. Triulzi
    • 12
  • N. Colombo
    • 13
  1. 1.Service d’Urgences Respiratoires, de Réanimation et Médecine Hyperbare, Centre AntiPoisonHôpital A. Calmette, Centre Hospitalier Régional UniversitaireLille CedexFrance
  2. 2.Hyperbaric DepartmentVirginia Mason Medical CenterSeattleUSA
  3. 3.Section of Pulmonary and Critical Care MedicineVirginia Mason ClinicSeattleUSA
  4. 4.Department of AnaesthesiologySUNY Health Science CenterSyracuseUSA
  5. 5.National Toxicology Information Centre“Clinica del Lavoro” Foundation Pavia Medical CentrePaviaItaly
  6. 6.2nd Division of CardiologyH. Niguarda Cà GrandaMilanItaly
  7. 7.1st Service of Anaesthesia and ReanimationH. Niguarda Cà GrandaMilanItaly
  8. 8.Milan Poison CentreH. Niguarda, Cà GrandaMilanItaly
  9. 9.Biochemical LabH. Niguarda Cà GrandaMilanItaly
  10. 10.Anaesthesia, Intensive and Hyperbaric Care DepartmentGaleazzi Orthopaedic InstituteMilanItaly
  11. 11.Child Neuropsychiatric ClinicH. San GerardoMonzaItaly
  12. 12.Department of NeuroradiologyScientific Institute San RaffaeleMilanItaly
  13. 13.Department of NeuroradiologyH. Niguarda Cà GrandaMilanItaly

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