Toxic Effects of Oxygen

  • G. De Martino
  • M. Luchetti
  • R. C. De Rosa
  • A. Marroni
  • G. Oriani
  • C. Longoni


Although oxygen has been present in the atmosphere for 5 billion years, it is believed that its concentration was infinitesimal until 2.5 billion years ago, when the first photosynthetic organisms appeared [1, 2]. The gradual increment of oxygen atmospheric concentration allowed further evolution for the animal species depending on an aerobic metabolism by enhancing the survival of those forms that had better protection against the increasing oxidative stress of the changing atmosphere [2].


Hyperbaric Oxygen Oxygen Toxicity Central Nervous System Toxicity Pulmonary Damage Normobaric Hyperoxia 
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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • G. De Martino
    • 1
  • M. Luchetti
    • 1
  • R. C. De Rosa
    • 1
  • A. Marroni
    • 2
  • G. Oriani
    • 3
  • C. Longoni
    • 4
  1. 1.Department of Anaesthesia, Intensive Care and Hyperbaric TherapyUniversity of Naples “Federico II”NaplesItaly
  2. 2.President DAN EuropeRoseto degli AbruzziItaly
  3. 3.Anaesthesia, Intensive and Hyperbaric Care DepartmentGaleazzi Orthopaedic InstituteMilanItaly
  4. 4.Anaesthesia and Reanimation ServiceZingonia (BG)Italy

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