Skip to main content

Hyperbaric Oxygen Therapy and Diabetic Problems

  • Chapter
Handbook on Hyperbaric Medicine

Abstract

Diabetes mellitus is the most frequent among the chronic metabolic diseases, and it is characterized by hyperglycaemia as well as alterations of the lipid and protein metabolism, which are associated with the absolute or relative absence of insulinic action and/or its secretion and by long-term complications affecting various organ systems. The data of prevalence and incidence are extremely variable depending on the investigative methods used and the geographical areas considered: In fact, the total prevalence of diabetes mellitus, both insulin-dependent and non insulin-dependent, varies from less than 0.1 to more than 4% in various studies [1]. Moreover, the epidemiological data are influenced by different prevalence in the various geographical areas and in the various populations, and also by the lack of a precise codification of the diagnostic criteria of this pathology. Diagnostic criteria accepted by WHO were established in 1980 [2].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. West KM (1978) Epidemiology of diabetes and its vascular lesions. Elsevier, New York

    Google Scholar 

  2. WHO Expert Committe on Diabetes Mellitus (1980) Second ReportWorld Health Organization. Technical Report Series 646, World Health Organization, Geneva

    Google Scholar 

  3. National Diabetes Data Group (1979) Classification and Diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1039: 19–79

    Google Scholar 

  4. Butterfield WJH (1964) Summary of results of the Bedford Diabetes Survey. Proc R Soc Med 57: 196

    PubMed  CAS  Google Scholar 

  5. Palumbo PJ, Elverback CR, Chu CP (1976) Diabetes Melittus Incidence, survorship and cause of death in Rochester, Minnesota,1945–1970. Diabetes 26: 66

    Google Scholar 

  6. Prior JAM, Davidson F (1966) The Epidemiolgy of Diabetes in Polynesians and Europeans in New Zealand and the Pacific. N Z Med J 65: 375

    PubMed  CAS  Google Scholar 

  7. Westlund K (1966) Incidence of diabetes mellitus in Oslo, Norway, 1925 to 1954, Report 11. Life Insurance Companies Institute for Medical Statistics: the Oslo city hospitals. Br J Prey Soc Med 3: 105

    Google Scholar 

  8. WHO (1965) Expert Committe Diabetes Mellitus Report. WHO Technical Reports Series No 310, WHO, Geneva

    Google Scholar 

  9. Jarrett RJ, Keen H (1975) Epidemiology of diabetes mellitus. In: Sussman KE, Metz RJ (eds) Fourth Edition Comm on Prof Ed American Diabetes Assocation

    Google Scholar 

  10. The Diabetes Control and Complication Trial Research Group (DCCT) (1993) The effect of intensive treatment of diabetes on the development of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977–986

    Article  Google Scholar 

  11. Garbay KH (1973) The sorbitol pathway and the complications of diabetes. N Engl J Med 288: 831–836

    Article  Google Scholar 

  12. Monnier VM, Vishanath V, Frank KE, Elmet CA, Danchot P, Kohn RR (1988) Relation Between complications of Type I diabetes mellitus and collagen linked fluorescence. N Engl J Med 37:456–461

    Google Scholar 

  13. Ziboh Va, Maruta H, Lords J, Cagle WD, Lucky W (1979) Increased biosynthesis of thromboxane in diabetic patients. Eur J Clin Invest 9: 223–228

    Article  PubMed  CAS  Google Scholar 

  14. Wilamson JR, Tilton RG, Chang K, Kilo C (1988) Basement membrane abnormalities in diabetes mellitus: relationship to clinical microangiopathy. Diabetes Metab Rev 4:339–370

    Article  Google Scholar 

  15. Knowles HC Jr (1974) Magnitude of the renal failure in diabetic patients. Kidney Int 6 (Supp11): 2–10

    Google Scholar 

  16. Proceedings of Ophthalmology Basic and Clinical Science Course (1983) - Section 4. Retina and Vitreous Am Acad of Ophalmology. 1833 Fillmore St San Francisco, California

    Google Scholar 

  17. Iarett RJ, Keen H, Grabaus AV (1979) The WHO multinational Study of Vascular Disease in Diabetics. 1. General descriptions. Diabetes Care 2: 175–186

    Google Scholar 

  18. Uusitupa M, Sitonen O, Aro O, Pyorala K (1985) Prevalence of heart coronary disease, left ventricular failure and hypertension in middle-aged newly diagnosed Type 2 (non-insulin dependent) diabetic subjects. Diabetologia 28: 22–26

    Article  PubMed  CAS  Google Scholar 

  19. Goto J, Fukuhara M (1968) Causes of death in 933 in diabetic autopsy cases. J Jpn Diabetic Soc 1: 197

    Google Scholar 

  20. Langerberg et al. (1971) Diabetes Mellitus mortality in the United States 1950–1967. In: Vital and health statistics. USA Natl Center for Health Statistics 20: 1–50

    Google Scholar 

  21. Schade DB, Santiago IV, Rizza RA (1983) Intensive insulin therapy. Excerpta Medica, Amsterdam

    Google Scholar 

  22. WHO Study Group (1985) Diabetes Mellitus. Technical Report Series 727. World Health Organisation, Geneva

    Google Scholar 

  23. Alberti KGMM, De Fronzo RA, Keen H, Zimmet P (eds) (1992) International Textbook of Diabetes Mellitus. Wiley, New York

    Google Scholar 

  24. Charcot JM (1868) Sur quelques arthropaties qui paraissent dépendre d’une lésion du cerveau ou de la moelle épinière. Arch Physiol Norm Pathol, 1: 161–178

    Google Scholar 

  25. Fernando DIS, Connor H, Boulton AJM (1991) The diabetic foot 1990. Diabetic Med 8: 82–85

    Article  PubMed  CAS  Google Scholar 

  26. Nathan DM (1993) Long-term complications of diabetes mellitus. N Engl J Med 328: 2676–2685

    Article  Google Scholar 

  27. Levin ME, O’Neal LW, Bowker JH (1993) The diabetic foot, 5th edn. Mosby-Year Book, Mosby, St. Louis

    Google Scholar 

  28. Frykberg RG (1991) The high risk foot in diabetes mellitus. Churchill Livingstone, London

    Google Scholar 

  29. Huse DM, Oster G (1989) The economic costs of NIDDM. JAMA 262: 2708–2713

    Article  PubMed  CAS  Google Scholar 

  30. National Diabetes Advisory Board (1987) The national long-range plan to combat diabetes. Washington, DC, U.S. Govt. Printing Office (DHHS Publ. no. 87–1587), p 24

    Google Scholar 

  31. Kacy S, Wolma FJ, Flye MW (1982) Factors affecting the results of below knee amputation in patients with and without diabetes. Surg Gynecol Obstet 156: 513–518

    Google Scholar 

  32. Charcot JM (1991) Lower extremity amputation among persons with diabetes mellitus - Washington 1988. MMWR 40, 43, 737–739

    Google Scholar 

  33. Levin ME (1988) The diabetic foot: pathophysiology, evaluation and treatment. In: The diabetic foot. Levin ME., O’Neal LW (eds) Mosby, St. Louis, pp 16–17

    Google Scholar 

  34. Bodily KC, Burgess EM (1983) Contralateral limb and patient survival after leg amputation. Am J Surg 146: 280–282

    Article  PubMed  CAS  Google Scholar 

  35. Mandrup-Poulsen T, Steen Jensen J (1982) Mortality after major amputation following gangrene of the lower limb. Acta Orthop Scand 53: 879–885

    Article  PubMed  CAS  Google Scholar 

  36. Kahn O, Wagner W, Bessmann AN (1974) Mortality of diabetic patients treated surgically for lower limb infection and/or gangrene. Diabetes 23: 287–292

    PubMed  CAS  Google Scholar 

  37. Silbert S (1952) Amputation of the lower extremity in diabetes mellitus: follow-up of 294 cases. Diabetes 1: 297–299

    PubMed  CAS  Google Scholar 

  38. Smith D, Weinberger M, Katz B (1987) A controlled trial to increase office visits and reduce hospitalizations of diabetic patients. J Gen Intern Med 2: 232–238

    Article  PubMed  CAS  Google Scholar 

  39. Boulton AIM, Connor H (1988) The diabetic foot 1988. Diabetic Med 5: 796–798

    Article  PubMed  CAS  Google Scholar 

  40. Edmonds ME, Blundell MP, Morris ME, Thomas EM, Cotton LT, Watkins PJ (1986) Improved survival of the diabetic foot: the role of a specialized foot clinic. Q J Med 60: 763–771

    PubMed  CAS  Google Scholar 

  41. Davidson JK,Alogna M, Goldsmith M, Borden J (1981) Assessment of program effectiveness at Grady Memorial Hospital, Atlanta. In: Educating diabetic patients. Steiner G., Lawrence P.A., (eds) Springer, Berlin Heidelberg New York, pp 329–348

    Google Scholar 

  42. Campbell DR (1991) In: Frykberg RG (ed) Diabetic vascular disease 3, pp 33–47. The high risk foot in diabetes mellitus. Churchill Livingstone, London

    Google Scholar 

  43. Reiber GE, Pecoraro RE, Koespell TD (1992) Risk factors for amputation in patients with diabetes mellitus. Ann Inter Med 117: 97–105

    CAS  Google Scholar 

  44. Flyn MD, Tooke JE (1992) Aetiology of diabetic foot: a role for microcirculation? Diabetic Med 9: 320–329

    Article  Google Scholar 

  45. Lo Gerfo FW, Coffman JD (1984) Vascular and microvascular disease of the foot in diabetes. Implications for foot care. N Engl J Med 311: 1615–1619

    Article  Google Scholar 

  46. Siperstein MD, Unger RH, Madison LL (1968) Studies of muscle capillary basement membranes in normal subjects, diabetic and prediabetic patients. J Clin Invest 47: 1973–1999

    Article  PubMed  CAS  Google Scholar 

  47. Friederici HHR, Tucker WR, Schwartz TB (1960) Observations on small blood vessels of skin in the normal and in diabetic patients. Diabetes 15: 233–250

    Google Scholar 

  48. Goldenberg SG, Alex M, Joshi RA, Blumenthal HT (1959) Nonatheromatous peripheral vascular disease of the lower extremity in diabetes mellitus. Diabetes 8: 261–273

    PubMed  CAS  Google Scholar 

  49. Parving HH, Rasmussen SM (1973) Transcapillary escape rate of albumin and plasma volume in short-and long-term juvenile diabetics. Scand J Clin Lab Invest, 32: 81–87

    Article  CAS  Google Scholar 

  50. Clavers B, Etrwiler D, Michael AF (1981) Albumin deposition in dermal capillary basement membrane in insulin-dependent diabetes mellitus: a preliminary report. Diabetes 30: 275–278

    Article  Google Scholar 

  51. McMillan DE (1993) The diabetic foot. In: Levin ME, O’Neal LW, Bowker JH (eds) Hemorheology, 5th edn. The diabetic foot. Mosby, St. Louis, pp 5, 115–133

    Google Scholar 

  52. Mathieu D, Coget JM, Wattel F (1984) Erythrocyte filterability and hyperbaric oxygen therapy. Med Sub Hyperb 3: 100–104

    Google Scholar 

  53. Nemiroff PM (1988) Synergistic effects of pentoxifylline and hyperbaric oxygen on skin flaps. Arch Otolaryngol Head Surg 114: 977–981

    Article  CAS  Google Scholar 

  54. Archer AG, Roberts VC, Watkins PJ (1984) Blood flow patterns in painful diabetic neuropathy. Diabetologia 27: 563–571

    Article  PubMed  CAS  Google Scholar 

  55. Delbridge L, Ctercteko G, Fowler C (1985) The aetiology of diabetic neuropathic ulceration of the foot. Br J Surg 72: 1–6

    Article  PubMed  CAS  Google Scholar 

  56. Sims DS, Cavanagh PR, Ulbrecht JS (1988) Risk factors in the diabetic foot. Phys Ther 68: 1887–1902

    PubMed  Google Scholar 

  57. Ward JD (1982) The diabetic leg. Diabetologia 22: 141–147

    Article  PubMed  CAS  Google Scholar 

  58. Ward JD, Simms JM, Knight G (1983) Venous distension in the diabetic neuropathic foot (physical sign of arteriovenous shunting). J R Soc Med 76: 1011–1013

    PubMed  CAS  Google Scholar 

  59. Edmonds ME, Roberts VC, Watkins PJ (1982) Blood flow in the diabetic neuropathic foot. Diabetologia 22: 9–15

    Article  PubMed  CAS  Google Scholar 

  60. Boulton AJM, Scarpello JHB, Ward JD (1982) Venous oxygenation in the diabetic neuropathic foot. Evidence of arteriovenous shunting ? Diabetologia 22: 6–8

    Article  PubMed  CAS  Google Scholar 

  61. Edmonds ME, Morrison N, Lawes JW, Watkins PJ (1982) Medial arterial calcification in diabetes mellitus. Br Med J 284: 928–930

    Article  CAS  Google Scholar 

  62. Scarpello JHB, Martini TRP, Ward JD (1980) Ultrasound measurements of pulse-wave velocity in the peripheral arteries of diabetic subjects. Clin Sci 58: 53–57

    PubMed  CAS  Google Scholar 

  63. Emanuele MA, Buchanan BJ, Abraira C (1981) Elevated leg, systolic pressure and arterial calcification in diabetic occlusive vascular disease. Diabetes Care 4, 289–292

    Article  PubMed  CAS  Google Scholar 

  64. Barnes HB, Kaiser GC, Wilman VL (1971) Blood flow in the diabetic leg. Circulation 43: 391–394

    Google Scholar 

  65. Bird AD, Tefler MB (1965) Effect of hyperbaric oxygen on limb circulation. Lancet I: 355–357

    Article  Google Scholar 

  66. Edmonds ME, Watkins PJ (1992) The diabetic foot in Alberti KGMM, De Fronzo RA, Keen H, Zimmet P (eds) International texbook of diabetes mellitus. John Wiley, New York, pp 1537–1538

    Google Scholar 

  67. Spierings ECH, Saxena PR (1979) Effect of Ergotamine on cranial ateriovenous shunting in experiments with constant flow perfusion. Eur Pharmacol 56: 31–37

    Article  CAS  Google Scholar 

  68. Edmonds ME, Archer AG, Watkins PJ (1983) Ephedrine, a new treatment for diabetic neuropathic oedema. Lancet I: 548–551

    Article  Google Scholar 

  69. Letaucher C, Bardoux J, Frenaux B (1975) Les désarterialisations déedieuses dans le traitement des troubles trophiques de l’acropathie ulcero-mutilante. Nouvelle Presse Med 4: 2325–2326

    Google Scholar 

  70. Edmonds ME, Nicolaides KH, Watkins PJ (1986) Autonomic neuropathy and diabetic foot ulceration. Diabetic Med 3:56–59

    Article  PubMed  CAS  Google Scholar 

  71. Hunt JA (1992) Foot infections in diabetes are rarely due to a single microorganism. Diabetic Med 9, 749–752

    Article  PubMed  CAS  Google Scholar 

  72. Louie TJ, Bartlett JG, Tally FP, Gorbach SL (1976) Aerobic and anaerobic bacteria in diabetic foot ulcers. Ann Intern Med 85: 461–463

    PubMed  CAS  Google Scholar 

  73. Wallin RJ, Gubliner SH (1964) Treatment of anaerobic infections with hyperbaric oxygen. Surg Clin North Am 44: 107–112

    Google Scholar 

  74. Pecoraro RE (1991) The nonhealing diabetic ulcer–a major cause for limb loss. Prog Clin Biol Res 365: 27–43

    PubMed  CAS  Google Scholar 

  75. Pentinnen, Niinikovski J, Kulonen E (1972) Hyperbaric oxygenation and fracture healing. A biochemical study with rats. Acta Chir Scand 138: 39–43

    Google Scholar 

  76. Morrey BF (1979) Hyperbaric oxygen and chronic osteomyelitis. Clin Orthop 144: 121–127

    PubMed  Google Scholar 

  77. Davis JC, Neekmann JD, Delee JC, Buckwold FJ (1986) Chronic nonhematogenous osteomyelitis treated with adjuvant hyperbaric oxygen. J Bone Joint Surg 68A: 1210–1217

    PubMed  CAS  Google Scholar 

  78. Baroni G, Porro T, Faglia E, Pizzi G, Mastropasqua A, Oriani G, Favales F (1987) Hyperbaric Oxygen in Diabetic Gangrene Treatment. Diabetes Care 10 (1): 81–86

    Article  PubMed  CAS  Google Scholar 

  79. Wagner FW (1981) The dysvascular foot: a system for diagnosis and treatment. Foot Ankle 2: 64–122

    PubMed  Google Scholar 

  80. Jeffcoate WJ, Macfarlane RM, Fletcher EM (1993) The description and classification of diabetic foot lesions. Diabetic Med 10: 676–679

    Article  PubMed  CAS  Google Scholar 

  81. Ameli FM, Byrne P, Provan JL (1989) Selection of amputation level and prediction of healing using transcutaneous tissue oxygen tension (Ptc O2). J Cardiovasc Surg 30: 220–224

    CAS  Google Scholar 

  82. Boulton AIM (1988) The diabetic foot. Med Clin North Am 72: 1513–1530

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer-Verlag Italia, Milano

About this chapter

Cite this chapter

Calia, P., Quarantiello, A., Faglia, E., Favales, F., Oriani, G., Michael, M. (1996). Hyperbaric Oxygen Therapy and Diabetic Problems. In: Oriani, G., Marroni, A., Wattel, F. (eds) Handbook on Hyperbaric Medicine. Springer, Milano. https://doi.org/10.1007/978-88-470-2198-3_17

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2198-3_17

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2200-3

  • Online ISBN: 978-88-470-2198-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics