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Functional MRI pp 119-124 | Cite as

Localization of Primary Motor Cortex in Patients with Frontal-parietal Neoplasms: an fMRI Study

  • A. Righini
  • O. de Divitiis
  • A. Prinster
  • D. Spagnoli
  • I. Appollonio
  • L. Bello
  • P. Scifo
  • G. Tomei
  • R. Villani
  • F. Fazio
  • M. Leonardi
Conference paper
Part of the Syllabus book series (SYLLABUS)

Abstract

Functional magnetic resonance imaging (fMRI), which uses BOLD (blood oxygenation level dependent contrast) technique, allows the identification of physiologically activated brain areas by means of a local and transient magnetic resonance (MR) signal increase [l]. The physical and physiological bases of the observed signal changes are not totally understood. The most accepted theory associates a local decrease in deoxyhemoglobin concentration within the venous microcirculation with the MR signal increase detected during brain activation [2].

Keywords

Primary Motor Cortex Precentral Gyrus Cavernous Angioma Magnetic Susceptibility Artifact Blood Oxygenation Level Dependent Contrast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Kwong KK, Belliveau JW, Chesier DA et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89: 5675–5679PubMedCrossRefGoogle Scholar
  2. 2.
    Ogawa S, Tank D, Menon R, Ellermann J, Kim S, Markle H, Ugurbil K (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89: 5951–5955PubMedCrossRefGoogle Scholar
  3. 3.
    Rao S, Binder JR, Bandettini BS et al (1993) Functional magnetic resonance imaging of complex human movements. Neurology 43: 2311–2318PubMedGoogle Scholar
  4. 4.
    Tyszka J, Grafton S, Chew W, Woods R, Colletti P (1994) Parceling of mesial frontal motor areas during ideation and movement using functional magnetic resonance imaging at 1.5 Tesla. Ann Neurol 35: 746–749PubMedCrossRefGoogle Scholar
  5. 5.
    Daniels DL, Yetkin ZF, Mark LP, Naughton VM (1994) Comparison of Functional MR Imaging and Anatomic Methods for Locating the Sensorymotor Cortex. Radiology 193: 186Google Scholar
  6. 6.
    Yousry T, Schmid U, Jassoy A et al (1995) Topography of the cortical motor hand area: prospective study with functional MR imaging and direct motor mapping at surgery. Radiology 195: 23–29PubMedGoogle Scholar
  7. 7.
    Jack C, Thompson RM, Butts RK et al (1994) Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and invasive cortical mapping. Radiology 190: 85–92PubMedGoogle Scholar
  8. 8.
    Howard R, Alsop D, Detre J, Listerud J et al (1994) Functional MRI of Regional Brain Activity in Patients with Intracerebral Gliomas and AVMs prior to Surgical or Endovascular Therapy. [Abstract] Society of Magnetic Resonance 2nd meeting, August, 701Google Scholar
  9. 9.
    Frahm J, Merboldt K, Haenicke W, Kleinschmidt A, Boecker H (1994) Brain or vein-oxygenation or flow? On signal physiology in functional MRI of human brain activation. NMR Biomed 7: 45–53PubMedCrossRefGoogle Scholar
  10. 10.
    Righini A, Pierpaoli C, Barnett AS, Waks E, Alger JR (1995) Blue blood or black blood: R, effects in gradient echo echo planar functional neuroimaging. Magn Reson Imag 13: 369–378Google Scholar
  11. 11.
    Constable R, McCarthy G, Allison T, Anderson A, Gore J (1993) Functional brain imaging at 1.5 T using conventional gradient echo MR imaging techniques. Magn Reson Imag 11: 451–459CrossRefGoogle Scholar
  12. 12.
    Edelman R, Siewert B, Darby D, Thangaraj V, Nobre A, Mesulam M, Warach S (1994) Qualitative mapping of cere-bral blood flow and functional localization with echo planar MR imaging and signal targeting with alternating radio-frequency. Radiology 192: 513–520PubMedGoogle Scholar
  13. 13.
    Duyn J, Mattay V, Sexton R, Sobering G, Barrios F, Liu G, Frank J, Weinberger D, Moonen C (1994) 3-Dimensional functional imaging of human brain using echo-shifted FLASH MRI. Magn Reson Med 32: 150–155Google Scholar

Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • A. Righini
    • 1
  • O. de Divitiis
    • 2
  • A. Prinster
    • 3
  • D. Spagnoli
    • 2
  • I. Appollonio
    • 4
  • L. Bello
    • 2
  • P. Scifo
    • 3
  • G. Tomei
    • 2
  • R. Villani
    • 2
  • F. Fazio
    • 3
  • M. Leonardi
    • 1
  1. 1.Neuroradiology DepartmentsIRCCS Ospedale Maggiore-PoliclinicoMilanItaly
  2. 2.Neurosurgery DepartmentsIRCCS Ospedale Maggiore-PoliclinicoMilanItaly
  3. 3.INB-CNR, IRCCS HS RaffaeleMilanItaly
  4. 4.Neurology DepartmentOspedale S. GerardoMonzaItaly

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