Functional MRI pp 105-110 | Cite as

PRESTO, a Rapid 3D Approach for Functional MRI of Human Brain

  • C. T. W. Moonen
  • P. van Gelderen
  • N. Ramsey
  • G. Liu
  • J. H. Duyn
  • J. Frank
  • D. R. Weinberger
Part of the Syllabus book series (SYLLABUS)


Ogawa et al. [1, 2] proposed in 1990 that physiological information related to neuronal activity can be incorporated in functional magnetic resonance imaging (fMRI) based on changes in the concentration of deoxyhemoglobin in blood (blood oxygenation level dependent, or BOLD effect). As compared to positron emission tomography (PET) and single photon emission computed tomography (SPECT), BOLD fMRI offers substantial advantages: minimal discomfort, no exposure to ionizing radiation and excellent spatial and temporal resolution. Several studies have now demonstrated that sensory and language functions can be mapped with fMRI.


Single Photon Emission Compute Tomography Echo Planar Imaging Gradient Echo Bold fMRI Bold Signal Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • C. T. W. Moonen
    • 1
  • P. van Gelderen
    • 1
  • N. Ramsey
    • 2
  • G. Liu
    • 1
  • J. H. Duyn
    • 3
  • J. Frank
    • 3
  • D. R. Weinberger
    • 2
  1. 1.NIH In Vivo NMR Research CenterBEIP, NCRR, Building 10, Room B1D-125BethesdaUSA
  2. 2.Clinical Brain Disorders BranchNIMH, NIH, 2700 Martin Luther King Jr. Avenue, S.EWashingtonUSA
  3. 3.Laboratory of Diagnostic Radiology Research ProgramOIR, NIH, BethesdaMarylandUSA

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