Functional MRI Brain Mapping Prior to Craniotomy or Radiosurgery: Initial Clinical Experience
The primary motor, sensory, visual, and language regions of the cerebral cortex can be identified using functional magnetic resonance imaging (fMRI) techniques. Identification of these cortical regions is a valuable tool for differentiating patients that may benefit from surgery from those in which focused radiotherapy (i.e. radiosurgery) is best. A variety of lesions that are located near primary cortical areas have the potential for neurologic deficit following craniotomy and surgery. Although neurologic deficits may arise from radiosurgical techniques, in general these methods have somewhat better success in treating lesions near primary eloquent cortex with minimal damage to normal brain tissue. In this investigation functional MRI applications were evaluated to provide a battery of fMRI paradigms capable of activating eloquent brain cortex adjacent to sites of various pathologic processes such as cerebral gliomas and arteriovenous malformations.
KeywordsMotor Cortex Arteriovenous Malformation Primary Motor Cortex Precentral Gyrus Word Production
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