Ulcerative jejunoileitis

  • G. R. Corazza
  • M. Di Stefano
  • M. A. Pistoia


Ulcerative jejunoileitis is a rare condition characterized by the presence of multiple and transverse ulcerations located in the jejunum, the ileum or both, with consequent scarring that can lead to narrow strictures of the intestinal wall. This condition has been considered to be a complication of adult celiac disease for 30 years, since the report of a case in which celiac disease had been diagnosed with certainty long before the development of small intestinal ulcerations. Very recently, ulcers of the first and second part of the duodenum have also been found in two very young celiac children. The nosology of this condition is today very confused. Even when coupled with villous atrophy, the dependence on celiac disease may be questionable in patients who do not respond to gluten withdrawal.


Celiac Disease Villous Atrophy Adjacent Mucosa Refractory Celiac Disease Adult Celiac Disease 
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Suggested reading

  1. Bayless TM, Kapelowitz RF, Shelley WM, Ballinger WF, Hendrix TR (1967) Intestinal ulceration — a complication of celiac disease. N Engl J Med 276:996–1002PubMedCrossRefGoogle Scholar
  2. Green JA, Barkin JS, Gregg PA, Kohen K (1993) Ulcerative jejunitis in refractory celiac disease: enteroscopic visualization. Gastrointest Endosc 39:584–585PubMedCrossRefGoogle Scholar
  3. Losowsky MS (1995) Ulcerative jejunoleitis-nosological, morphological and clinical aspects. In: Gasbarrini G, Corazza GR, Alessandrini A (eds) Morfologia dell’in-testino tenue.Editrice Compositori, Bologna, pp 79–85Google Scholar

Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • G. R. Corazza
  • M. Di Stefano
  • M. A. Pistoia

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