Abstract
Until the early 1940s, before the introduction into clinical practice of neuromuscular blocking drugs, the adequacy of the depth of anaesthesia could be assessed by observing patients’ reactions to surgical stimuli in terms of gross movements, breathing activity, reflexes, and muscular tone. Furthermore, the use of highly soluble volatile agents made it possible to distinguish clearly between different levels of anaesthesia, which were accomplished quite slowly. In those circumstances, an excessive depth of anaesthesia was the main danger.
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Ori, C., Roncarati, A., Rizzi, S. (2004). Awareness during anaesthesia: incidence and clinical and legal aspects. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2189-1_10
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DOI: https://doi.org/10.1007/978-88-470-2189-1_10
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