Abstract
Bone diseases are often present in subjects affected by thalassemia major and appear with different pathological features during growth or adult age [1], According to anatomopathological standards, the group of bone diseases observed during growth are characterized by cartilaginous lesions due mainly to both premature and asymmetrical fusion of the metaphyseal cartilage, while those observed in adults are expressed by skeleteal lesions [2–4]. In this paper we evaluate the lesions involving both the distal metaphysis of the femur and the proximal metaphysis of the tibia in thalassemic children between 8 and 11 years of age.
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References
Giuzio E, Bria M, Brancati C (1991) Le alterazioni scheletriche nella thalassemia major. GIOT 17: 277–283
Colavita M, Orazi C, Danza SM, Falappa P, Fabbri R (1987) Premature epiphyseal fusion and extramedullary hematopoiesis in thalassemia. Skeletal Radio 16: 533–538
Currarino G, Erlandom M (1964) Premature fusion of epiphysis in Cooley anemia. Bone Joint Surg 83: 656–664
Esposito L, Ferrara M, Furante A (1976) Rilievi sull’accrescimento staturale e sulle maturazione scheletrica sulla talassemia mayor in rapporto alia terapia emotrasfusiva. Pediatria 84: 235–246
Podda G, Fodde M, Pirastu GF (1987) Preliminari considerazioni sulle alterazioni scheletriche in pazienti affetti da talassemia major trattati con deferoxamina. Atti 3rd SIRMN, Cagliari, pp 311–315
Brill PW, Winchester P, Giardina PJ (1991) Deferoxamine - induced bone dysplasia in patients with thalassemia major. A JR 156: 561–565
Orzincolo C, Scutellari P, Castaldi G (1992) Growth plate injury of the long bones in treated pthalassemia. Skeletal Radiol 21: 39–44
De Virgillis S, Congia M, Frau F (1989) Deferoxamine-induced growth retardation in patients with thalassemia major. J Pediatr 113: 661
Model B, Berdoukas V (1984) The clinical approach to thalassaemia. Grune and Stratton New-York
Giuzio E, Bria M, Bisconte MG, Brancati C L’Osteopenia nei thalassemici politrasfusi. Nostra esperienza. Chir Organi Mov 76: 369–374
Giuzio E, Bria M, Misasi M, Brancati L (1991) Le dismetrie degli arti inferiori nella thalassemia major. GIOT [suppl] 129–132
Middlemiss GM, Raper A (1966) Skeletal changes in the haemoglobinopathies. J Bone Joint Surg [Br] 48: 693–702
Radici M, Galloni O (1977) Le alterazioni scheletriche nella malattia di Cooley. Arch Osp S Anna 20: 885–889
Ramazzina E, Nardi A, Luisetto G, Chiavilli F (1986) Metabolismo minerale e scheletrico nella beta talassemia. Atti Accad Sci Ferrara 63: [Suppl] 251–263
Puxeddu L, Floris G, Murras MC (1984) II metabolismo calcico nell’osteopatia talassemica. Ortop Traumatol Oggi 4
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© 1995 Springer-Verlag Berlin Heidelberg
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Giuzio, E., Bria, M., Romeo, F., Misasi, M., Brancati, C. (1995). Imaging, Ultrastructural Aspects, and Trace Elements in the Thalassemic Condrodystrophy. In: Andò, S., Brancati, C. (eds) Endocrine Disorders in Thalassemia. Springer, Milano. https://doi.org/10.1007/978-88-470-2183-9_9
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DOI: https://doi.org/10.1007/978-88-470-2183-9_9
Publisher Name: Springer, Milano
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