Imaging, Ultrastructural Aspects, and Trace Elements in the Thalassemic Condrodystrophy

  • E. Giuzio
  • M. Bria
  • F. Romeo
  • M. Misasi
  • C. Brancati


Bone diseases are often present in subjects affected by thalassemia major and appear with different pathological features during growth or adult age [1], According to anatomopathological standards, the group of bone diseases observed during growth are characterized by cartilaginous lesions due mainly to both premature and asymmetrical fusion of the metaphyseal cartilage, while those observed in adults are expressed by skeleteal lesions [2–4]. In this paper we evaluate the lesions involving both the distal metaphysis of the femur and the proximal metaphysis of the tibia in thalassemic children between 8 and 11 years of age.


Thalassemic Patient Thalassemia Major Femoral Metaphysis Distal Metaphysis Ultrastructural Aspect 
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© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • E. Giuzio
  • M. Bria
  • F. Romeo
  • M. Misasi
  • C. Brancati

There are no affiliations available

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