Abstract
Recent reports demonstrate a reduction of bone mineral content on the distal radius in thalassemic patients over the age of 9 years [1–3]. The possibility of accurately measuring bone density at the level of the lumbar spine and femur has significantly improved the sensitivity of measurements in thalassemic patients with primary and secondary amenorrhea, using double X-ray absorptiometry (DXA), to investigate the incidence of osteopenia and its correlation with age, duration of amenorrhea, and biochemical markers of calcium metabolism.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bagni B, De Sanctis V (1986) Densitometria ossea in pazienti talassemiche con regolari cicli mestruali, amenorrea primaria e secondaria. In: De Sanctis V (ed) La maturazione sessuale nella beta-talassemia major. International Meeting, Sept 12–13, Ferrara, pp 149–158
Ramazzina E, Nardi A, Luisetto G (1986) Metabolismo minerale e scheletrico nell beta-talassemia omozigote. In: De Sanctis V (ed) La maturazione sessuale nella beta-talassemia major. International Meeting, Sept 12-13, Ferrara, pp 249–263
Iolascon G, Ronca D, Crusco R (1989) La densitometria ossea computerizzata nel follow-up della malattia di Cooley. 15th National Congress of A.I.E.OP, April 26-30, Turin
Drinkwater B, Nilson K, Chesnut TCH (1984) Bone mineral content of amenorrheic and eumenorrheic athletes. N Engl J Med 311: 277–281
Cann CE, Martin MC, Genant HK (1984) Decreased spinal mineral content in amenorrheic women. J 251: 626–629
De Sanctis V, Atti G, Lucci M (1980) Endocrine assessment of hypogonadism in patients affected by thalassemia major. Clin Lab 10: 663–670
Propper RD, Button LN, Nathan DG (1980) New approaches to the transfusion management of thalassemia. Blood 55: 55–61
Aldouri MA, Wonker B, Hoffbrand AV (1987) Iron state and hepatic disease in patients with thalassaemia major, treated with long-term subcutaneous desferrioxamine. J Clin Pathol 40: 1353–1359
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Bagni, B., De Sanctis, V., Bagni, I., Cavallini, A.R., Bonaccorsi, G., Vullo, C. (1995). Osteopenia in Thalassemic Patients with Primary and Secondary Amenorrhea. In: Andò, S., Brancati, C. (eds) Endocrine Disorders in Thalassemia. Springer, Milano. https://doi.org/10.1007/978-88-470-2183-9_8
Download citation
DOI: https://doi.org/10.1007/978-88-470-2183-9_8
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2185-3
Online ISBN: 978-88-470-2183-9
eBook Packages: Springer Book Archive