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Thyroid Function in Thalassemia major

  • A. Filosa
  • S. Di Maio
  • A. Saviano
  • S. Aponte

Abstract

Hypothyroidism is one of the most frequent endocrinological complications in thalassemic patients [1]. Lack or delay of puberty [2-4], hypoparathyroidism [5], and insulin-dependent diabetes mellitus [6] are concomitant endocrine abnormalities in such patients. It is reported in the literature that these complications are due to iron over load at the hypothalamic and/or pituitary level and/or at the glandular level [7-9]. Nevertheless, the cause of hypothyroidism in thalassemic patients is unclear still in fact, the results presented in the literature show a broad spectrum of possible alterations [6, 9].

Keywords

Ferritin Level Thalassemic Patient Thalassemia Major Pituitary Level Thyroid Hormone Serum Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • A. Filosa
  • S. Di Maio
  • A. Saviano
  • S. Aponte

There are no affiliations available

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