Pituitary-Thyroid Function in Children with β-Thalassemia major
Long-term survival of patients with thalassemia major has been improved by regular transfusion and chelation therapy . However, multiple endocrine disturbances, including thyroid dysfunction, attributed to the chronic transfusional iron overload and causing morbidity and mortality in thalassemic patients are still a major problem [2, 3]. The purpose of the present study was to determine the incidence of pituitary-thyroid dysfunction and its relationship to various clinical and laboratory measurements in thalassemic patients.
KeywordsSerum Ferritin Level Chelation Therapy Thalassemic Patient Thalassemia Major Pretransfusional Hemoglobin Level
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