Antarctic Fish Immunoglobulins: Preliminary Data on Structure and Antibody Specificity

  • Maria Rosaria Coscia
  • Umberto Oreste


Fish immunoglobulins resemble mammalian IgM in terms of size (five Ig domains), carbohydrate composition of the heavy chain (12–16%), and polymeric assembly of the basic unit H2L2 (tetrameric in bony fish and pentameric in cartilaginous fish). However, the overall features of the mammalian secondary immune response (rise in titre, shift to high affinity antibodies, isotypic switch) are not found in fish [1],


Antarctic Fish Anisakis Simplex Fast Performance Liquid Chromatography Nematode Protein Contracaecum Osculatum 
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Copyright information

© Springer-Verlag Italia 1998

Authors and Affiliations

  • Maria Rosaria Coscia
    • 1
  • Umberto Oreste
    • 1
  1. 1.Institute of Protein Biochemistry and EnzymologyCNRNaplesItaly

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