Abstract
Dilated cardiomyopathy was defined as a heart muscle disease of unknown cause characterized by left ventricular or biventricular dilatation and impaired systolic function [1]. The natural history of the disease is difficult to ascertain, as asymptomatic ventricular dilatation and dysfunction may be present for long periods. Prognosis of the disease from the onset of symptoms was generally described as poor [2–3]. These retrospective studies usually analysed patients with advanced heart failure, who have been mostly evaluated in a period preceding the widespread use of echocardiography as a diagnostic tool, in tertiary referral centers. Whether earlier diagnosis and careful follow-up would substantially impact on the reportedly dire prognosis was at the moment unclear. These considerations prompted a cooperative effort involving 15 Italian centers in a multicenter Registry, which started in January 1986. The aim of this registry was the prospective study of the natural history of dilated cardiomyopathy, with particular attention to early manifestations of disease.
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References
Report of the WHO/ISFC Task Force (1980) on the definition and classification of cardiomyopathies. Br Heart J 44:672–673
Fuster V, Gersh BJ, Giuliani ER, Tajik AJ, Branderburg RO, Frye RL (1981) The natural history of idiopathic dilated cardiomyopathy. Am J Cardiol 47:525–531
Gavazzi A, Lanzarini L, Cornalba C, Desperati M, Raisaro A, Angoli L, De Servi S, Specchia G (1984) Dilated (congestive) cardiomyopathy. Follow up study of 137 patients. G Ital Cardiol 11:492–498
Diaz RA, Obasohan A, Oakley CM (1987) Prediction of outcome in dilated cardiomyopathy. Br Heart J 58:393–399
Ikram H, Williamson HG, Won IG, Wells EJ (1987) The course of idiopathic dilated cardiomyopathy in New Zealand. Br Heart J 57:521–527
Komajda M, Jaist JP, Reeves F, Goldfarb B, Boubour JB, Juilleres Y, Lanfranchi I, Peycelon P, Geslin P, Carie D, Grosgogeat Y (1990) Factors predicting mortality in idiopathic dilated cardiomyopaty. Eur Heart J 11:824–831
Sugrue DD, Rodeheffer RJ, Codd MB, Ballard DJ, Fuster V, Gersh BR (1992) The clinical course of idiopathic dilated cardiomyopathy: a population-based study. Ann Intern Med 117:-23
Redfield MM, Gersh BJ, Bailey KR, Ballard DJ, Rodeheffer RJ (1993) Natural history of idiopathic dilated cardiomyopathy: effect of referral bias and secular trend. J Am Coll Cardiol 22:1921–1926
Di Lenarda A, Secoli G, Perkan A, Gregori D, Lardieri G, Pinamonti B, Sinagra G, Zecchin M, Camerini F (1994) Changing mortality in dilated cardiomyopathy. Br Heart J 72 [suppl]:S46–S51
Sahn DJ, De Maria AN, Kisslo J, Weyman A (1976) The committee on M-mode standardization of the American Society of Echocardiography: Recommendations regarding quantitation in M-mode echocardiography. Results of a survey of echocardiographic measurements. Circulation 58:1072–1083
Folland ED, Parisi AF, Moynihan PF, Jones DR, Feldman CL, Tow DE (1979) Assessment of left ventricular ejection fraction and volumes by real-time two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques. Circulation 60:760–766
Aretz HT, Billingham ME, Edwards WD, Factor S, Fenoglio J, Olsen EG, Schoen F (1986) Myocarditis: a histopathologic definition and classification. Am J Cardiovasc Pathol 1:3–14
Hinkle L, Thaler J (1982) Clinical classification of cardiac deaths. Circulation 65:457–464
Codd MB, Sugrue DD, Gersh BJ, Melton LJ (1989) Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. Circulation 80:564–572
Hosenpud JD, Novick RJ, Breen TJ, Keck B, Daily P (1995) The registry of the Internaitonal Society for Heart and Lung Transplantation: twelfth official report — 1995. J Heart Lung Transplant 14:805–815
Stevenson WG, Stevenson LW, Middlekauf HR, Fonarow GC, Hamilton MA, Woo MA, Saxon LA, Natterson PD, Steimle A, Waiden JA, Tillisch JH (1995) Improving survival for patients with advanced heart failure: a study of 737 consecutive patients. J Am Coll Cardiol 26:1417–1423
Waagstein F, Bristow MR, Swedberg K, Camerini F, Foxier MB, Silver MA, Gilbert EM, Johnson MR, Goss FG, Hjalmarson A (1993) Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Lancet 342:1441–1446
CIBIS Investigators and Committees (1994) A randomized trial of beta-blockade in heart failure. The cardiac insufficiency bisoprolol study (CIBIS). Circulation 90:1765–1773
Packer M, Bristow MR, Cohn JN, Colucci WS, Fowler MB, Gilbert EM, Shusterman NH (1996) The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 334:1349–1355
Goldman JH, Keeling PJ, Slade A, Elliot P, Caforio A, Poloniecki J, McKenna WJ (1995) The improved prognosis of idiopathic dilated cardiomyopathy in the era of modern therapeutics. J Am Coll Cardiol 25-1:386 (abs)
Dec GW, Fuster V (1994) Idiopathic dilated cardiomyopathy. N Engl J Med 331:1564–1575
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De Maria, R., Parolini, M., Italian Study Group on Cardiomyopathies (SPIC). (1998). The Italian Multicentric Study: Natural History of Dilated Cardiomyopathy. In: Camerini, F., Gavazzi, A., De Maria, R. (eds) Advances in Cardiomyopathies. Springer, Milano. https://doi.org/10.1007/978-88-470-2155-6_23
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DOI: https://doi.org/10.1007/978-88-470-2155-6_23
Publisher Name: Springer, Milano
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