Genetic Basis of Dilated Cardiomyopathy

  • J. A. Towbin
  • K. R. Bowles
  • R. Ortiz-Lopez
  • Q. Wang
Conference paper


Dilated cardiomyopathy (DCM) is a disease of the myocardium characterized by dilation and impaired function of the left ventricle or both ventricles in the absence of coronary artery disease, valvular abnormalities, pericardial disease, and specific myocardial inflammatory diseases including myocarditis [1]. In general, systolic dysfunction is the main clinical feature with resultant signs and symptoms of congestive heart failure. Although the cause of DCM is usually not known, familial transmission is found in some cases. In this manuscript, the current understanding of the genetic causes of DCM is described.


Muscular Dystrophy Dilate Cardiomyopathy Duchenne Muscular Dystrophy Myotonic Dystrophy Barth Syndrome 
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Copyright information

© Springer-Verlag Italia 1998

Authors and Affiliations

  • J. A. Towbin
  • K. R. Bowles
  • R. Ortiz-Lopez
  • Q. Wang

There are no affiliations available

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