Review of the Results of Previous Phase II, Magnetic Resonance Imaging-monitored Clinical Trials

  • P. Soelberg Sørensen
Conference paper
Part of the Topics in Neuroscience book series (TOPNEURO)


During the last decade magnetic resonance imaging(MRI) has become a useful tool for monitoring efficacy of new treatments in multiple sclerosis (MS). Serial MRI detects 10 times more disease activity than does the registration of clinical relapses in patients with relapsing-remitting MS or in the early phase of secondary progressive MS.[1, 2]. Consequently, MRI is a sensitive tool for monitoring therapeutically induced changes in disease activity which can be measured objectively and quantitatively compared to the subjective evaluation of clinical changes.


Magnetic Resonance Imaging Multiple Sclerosis Expanded Disability Status Scale Active Lesion Expanded Disability Status Scale Score 


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Copyright information

© Springer-Verlag Italia 1999

Authors and Affiliations

  • P. Soelberg Sørensen
    • 1
  1. 1.MS Research Unit, The Neuroscience CenterCopenaghen University Hospital, RigshospitaletCopenaghenDenmark

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