Dementias pp 77-101 | Cite as

Alzheimer’s Disease

  • A. Bianchetti
  • M. Trabucchi


Alzheimer’s disease (AD) is the most common of the dementing disorders. Once considered a rare disorder, AD is now recognized as a major cause of death and a growing public health problem. In 1907, Alois Alzheimer reported the first case of the illness that bears his name, a 51-year-old woman with progressive cognitive decline and behavioral changes associated with distinctive neuropathological features [1]. Much time has passed since then, however. Until recently, there has been widespread nihilism in the clinical approach to the demented patient. Most physicians believed that there was little reason to spend money or effort diagnosing diseases with no known risk factors, preventive measures or treatments [2]. However, a multidisciplinary effort has transformed this field, leading to a better understanding of the clinical presentation, risk factors, pathogenesis and treatment of the other degenerative dementias [3].


Alzheimer Disease Amyloid Precursor Protein Behavioral Disturbance Lewy Body Dementia Paired Helical fIlaments 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 1999

Authors and Affiliations

  • A. Bianchetti
  • M. Trabucchi

There are no affiliations available

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