Gastroesophageal Reflux and Nonspecific Hyperreactivity of Upper Aerodigestive Tract: Possible Correlations with Otorhinolaryngological Disorders

  • F. Filiaci
  • G. Zambetti
  • M. Luce
  • R. Romeo


Gastroesophageal reflux (GER), a common disorder of the upper digestive tract, is primarily caused by release of the lower esophageal sphincter associated with delayed gastric emptying, abnormal esophageal mucosal resistance, and increased irritative capacity of the refluxate [1]. A clinical classification divides GER into a typical form with the classic pyrosis and an atypical form [2]. Patients with respiratory symptoms fall into the latter atypical, or extraesophageal, form that characterizes the “silent” GER. [3]. In fact, the initial symptomatology is often characterized by a succession of symptoms (e.g. dysphagia, foreign body sensation, chronic throat clearing, hoarseness, cough, otalgia, obstructive apnea, and recurrent bronchitis and pneumonia) that suggest the direct involvement of the upper and lower airways.


Hiatal Hernia Gastroesophageal Reflux Lower Esophageal Sphincter Soft Palate Lower Airway 
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Copyright information

© Springer-Verlag Italia 1999

Authors and Affiliations

  • F. Filiaci
    • 1
  • G. Zambetti
    • 1
  • M. Luce
    • 1
  • R. Romeo
    • 1
  1. 1.Department of OtorhinolaryngologyUniversity of Rome La SapienzaRomeItaly

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