Gastroesophageal Reflux in Chronic Obstructive Pulmonary Disease

  • M. Lusuardi
  • C. F. Donner


The frequent association of gastroesophageal reflux (GER) and respiratory disorders, in particular asthma, chronic obstructive pulmonary disease (COPD), chronic dry cough, cystic fibrosis and idiopathic pulmonary fibrosis, is well known [1–4]. In this short review, the terms COPD and chronic bronchitis will be used indifferently to indicate a clinical picture characterized by chronic productive cough (for at least two months a year in the past two years) and possible bronchial obstruction with a significant irreversible component. The incidence of GER in asthma ranges from 40% to 80% according to the series; the figures for chronic bronchitis are about 50%–60% [1, 5]. In the study of Ducoloné et al. [5], about 50% of patients with GER had no clinical complaint of GER (although half of these had cough and nocturnal dyspnea) while the other 50% had both digestive and respiratory symptoms. Among the 17 subjects with GER, 9 were on theophylline treatment, but only 2 received sympathomimetic agents [5].


Chronic Obstructive Pulmonary Disease Gastroesophageal Reflux Chronic Obstructive Pulmonary Disease Patient Idiopathic Pulmonary Fibrosis Lower Esophageal Sphincter 


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© Springer-Verlag Italia 1999

Authors and Affiliations

  • M. Lusuardi
    • 1
  • C. F. Donner
    • 1
  1. 1.Division of Pulmonary Disease, Salvatore Maugeri FoundationIRCCS, Rehabilitation InstituteVeruno (Novara)Italy

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