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Management of Acute Ischaemic Stroke

  • C. Fieschi
Conference paper

Abstract

Despite its dramatic incidence and prognosis, until few years ago, stroke was considered as the Cinderella of medicine. For both public and physicians, even neurologists, this pathology was unavoidable and untreatable. Fortunately, in the past decades this nihilistic attitude regarding stroke has been replaced by a more enthusiastic one. This is explained by research advances in pathophysiology of ischaemia and by the greater awareness of economic concerns about this pathology. The aim of experimental and clinical research is now to reduce mortality and stroke morbidity following stroke, and consequently to minimise costs.

Keywords

Stroke Unit Restore Blood Flow European Cooperative Acute Stroke Study Ischaemic Penumbra Stroke Symptom Onset 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Fieschi C, Argentino C, Lenzi GL et al (1989) Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours. J Neurol Sci 91:311–322PubMedCrossRefGoogle Scholar
  2. 2.
    Ginsberg MD, Pulsinelli WA (1994) The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke. Ann Neurol 36:553–554PubMedCrossRefGoogle Scholar
  3. 3.
    Astrup J, Siesjo BK, Symon L (1981) Thresholds in cerebral ischemia — the ischemic penumbra. Stroke 12:723–725PubMedCrossRefGoogle Scholar
  4. 4.
    The European Ad Hoc Consensus Group (1996) European strategies for early intervention in stroke. Cerebrovasc Dis 6:351–324Google Scholar
  5. 5.
    Langhorne P, Williams BO, Gilchrist W et al (1993) Do stroke units save lives? Lancet 342: 395–398PubMedCrossRefGoogle Scholar
  6. 6.
    Jørgensen HS, Nakayama U, Raaschou HA et al (1995) The effect of a stroke unit: reductions in mortality, discharge rate to nursing home, length of hospital stay, and cost. A community-based study. Stroke 26:1178–1182Google Scholar
  7. 7.
    The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group (1995) Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 33:1581–1587Google Scholar
  8. 8.
    Hacke W, Kaste M, Fieschi C et al (1995) Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA 274:1017–1025PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 1999

Authors and Affiliations

  • C. Fieschi
    • 1
  1. 1.Dept. of Neurological SciencesLa Sapienza University School of MedicineRomeItaly

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