As the brain is the most vulnerable vital organ, the clinical and socioeconomic importance of cerebral resuscitation is obvious. After the global brain ischaemia (GBI) of cardiac arrest (CA), the focal brain ischaemia (FBI) of stroke, or traumatic brain injury (TBI), we must aim for “good outcome” in terms of CPC 1 (cerebral performance category 1) (normal) or CPC 2 (moderate disability). In addition, we must learn to prevent long-term survival with “poor” outcome, i.e., CPC 3 (severe disability but conscious), CPC 4 (coma, persistent vegetative state), or CPC 5 (brain death or death). Thus, we must differentiate between overall and cerebral performance categories (OPC 1–5 vs CPC 1–5) [1].


Traumatic Brain Injury Cardiac Arrest Cereb Blood Flow Cerebral Performance Category Focal Brain Ischaemia 
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Copyright information

© Springer-Verlag Italia 1999

Authors and Affiliations

  • P. Safar
    • 1
  1. 1.Safar Centre for Resuscitation Research and Dept. of Anaesthesiology and Critical Care MedicinePittsburgh UniversityPittsburghUSA

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