Lone Atrial Fibrillation: What Is the Anatomical and the Electrophysiological Substrate?
Atrial fibrillation is commonly associated with a structural heart disease such as valvular disease, coronary artery disease, or dilated cardiomyopathy. Lone atrial fibrillation may be defined as a form of paroxysmal, persistent, or permanent atrial fibrillation with a “pure” electrophysiological substrate. But, does a pure lone atrial fibrillation really exist? To answer this question, it is important to investigate carefully both the anatomic and the electrophysiologic substrates, including all modulating factors that may increase the probability of induction of atrial fibrillation.
KeywordsAtrial Fibrillation Pulmonary Vein Paroxysmal Atrial Fibrillation Ectopic Beat Lone Atrial Fibrillation
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- 2.Allessie MA (1995) Reentrant mechanisms underlying atrial fibrillation. In: Zipes DP, Jalife J (eds) Cardiac electrophysiology: from cell to bedside, 2nd edn. Saunders, Toronto, pp 562–566Google Scholar
- 6.Bayès de Luna A, Cladellas M, Oter R, Torner P, Guindo J et al (1988) Interatrial conduction block and retrograde activation of the left atrium and paroxysmal supraventricular tachyarrhythmia. Eur Heart J 9:1112–1118Google Scholar
- 12.Attuel P, Pellegrin D, Gaston J (1989) Latent atrial vulnerability: new means of electrophysiologic investigations in paroxysmal atrial arrhythmias. In: Attuel P, Coumel P, Janse MJ (eds) The atrium in health and disease. Futura, Mt Kisco, NY, pp 159–200Google Scholar