Abstract
Atrial fibrillation is commonly associated with a structural heart disease such as valvular disease, coronary artery disease, or dilated cardiomyopathy. Lone atrial fibrillation may be defined as a form of paroxysmal, persistent, or permanent atrial fibrillation with a “pure” electrophysiological substrate. But, does a pure lone atrial fibrillation really exist? To answer this question, it is important to investigate carefully both the anatomic and the electrophysiologic substrates, including all modulating factors that may increase the probability of induction of atrial fibrillation.
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References
Frustaci A, Chimenti C, Bellocci F, Morgante E, Russo MA, Maseri A (1997) Histological substrate of atrial biopsies in patients with lone atrial fibrillation. Circulation 96:1180–1184
Allessie MA (1995) Reentrant mechanisms underlying atrial fibrillation. In: Zipes DP, Jalife J (eds) Cardiac electrophysiology: from cell to bedside, 2nd edn. Saunders, Toronto, pp 562–566
Jais P, Haissaguerre M, Dipen C, Chouairi S, Gencel L, Hocini M, Clementy J (1997) A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circulation 95:572–576
Papageorgiou P, Moahan K, Boyle N, Seifert MJ, Beswick P, Zebeda J, Epstein L, Josephson ME (1996) Site-dependent intra-atrial conduction delay. Relationship to initiation of atrial fibrillation. Circulation 94:384–389
Thomas SA, Schussler RB, Saffitz JE (1998) Connexins, conduction and atrial fibrillation. J Cardiovasc Electrophysiol 9:608–1007
Bayès de Luna A, Cladellas M, Oter R, Torner P, Guindo J et al (1988) Interatrial conduction block and retrograde activation of the left atrium and paroxysmal supraventricular tachyarrhythmia. Eur Heart J 9:1112–1118
Bagliani G, Meniconi L, Raggi F, Corea L (1998) Left origin of the atrial esophageal signal as recorded in the pacing site. Pacing Clin Electrophysiol 21 (I):18–24
Michelucci A, Padeletti L, Fradella GA (1982) Atrial refractoriness and spontaneous or induced atrial fibrillation. Acta Cardiol 37:333–341
Misier AR, Opthof T, van Hemel NM (1992) Increased dispersion of refractoriness in patients with idiopathic paroxysmal atrial fibrillation. J Am Coll Cardiol 19:1531–1535
Zipes DP, Mihalick MJ, Robbins GT (1983) Effect of selective vagal and stellate ganglionic stimulation on atrial refractoriness in man. Am J Cardiol 51:96–100
Satoh T, Zipes DP (1996) Unequal atrial stretch in dogs increases dispersion of refractoriness conducive to developing atrial fibrillation. J Cardiovasc Electrophysiol 7:833–842
Attuel P, Pellegrin D, Gaston J (1989) Latent atrial vulnerability: new means of electrophysiologic investigations in paroxysmal atrial arrhythmias. In: Attuel P, Coumel P, Janse MJ (eds) The atrium in health and disease. Futura, Mt Kisco, NY, pp 159–200
Cosio FG, Palacios J, Vidal JM (1983) Electrophysiologic studies in atrial fibrillation: slow conduction of premature impulses. A possible manifestation of the background for reentry. Am J Cardiol 51:122–130
Wyndham CRC, Amat-y-Leon F, Wu D, Denes P, Dhingra R, Simpson R, Rosen KM (1977) Effects of cycle length on atrial vulnerability. Circulation 55:260–271
Haïssaguerre M, Markus F, Fischer B, Clementy J (1994) Radiofrequency catheter ablation in unusual mechanisms of atrial fibrillation. J Cardiovasc Electrophysiol 5:743–751
Haïssaguerre M, Jaïs P, Shah D, Takahashi A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Metayer P, Clementy J (1998) Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339:659–666
Capucci A, Santarelli A, Boriani G (1992) Atrial premature beats coupling interval determines lone paroxysmal atrial fibrillation onset. Int J Cardiol 36:87–93
Alessi R, Nusynowitz M, Abildskov JA (1958) Nonuniform distribution of vagal effects on the atrial refractory period. Am J Physiol 194:406–410
Coumel P (1996) Autonomic influences in atrial tachyarrhythmias. J Cardiovasc Electrophysiol 7:999–1007
Rubart M, von der Lohe E (1998) Sex steroids and cardiac arrhythmia: more questions than answers. J Cardiovasc Electrophysiol 9:665–667
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© 2000 Springer-Verlag Italia
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Bagliani, G. et al. (2000). Lone Atrial Fibrillation: What Is the Anatomical and the Electrophysiological Substrate?. In: Raviele, A. (eds) Cardiac Arrhythmias 1999. Springer, Milano. https://doi.org/10.1007/978-88-470-2139-6_5
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DOI: https://doi.org/10.1007/978-88-470-2139-6_5
Publisher Name: Springer, Milano
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