What Is the Clinical and Prognostic Significance of High-Resting Sinus Rate?

  • F. Hernández-Bernal
  • L. Mantini
  • R. Latini
  • G. Zuanetti
  • A. P. Maggioni
Conference paper


The interest in alterations in the autonomic nervous system as useful markers for risk stratification in patients with acute myocardial infarction (MI) has grown steadily in the last few years [1]. The prognostic significance of non-invasive indexes of autonomic nervous system dysfunction, such as heart rate (HR) variability and baroreflex sensitivity, has been evaluated; however, the application of these techniques in clinical practice has been hindered by methodological and practical limitations so that their use is still mostly limited to a few centers. At the same time, it has become clear that simple and crude indexes of sympatheticparasympathetic balance as well as left ventricular function, such as HR or blood pressure, may play a major role in the risk stratification during the acute phase and at discharge [2–4].


Heart Rate Variability Acute Myocardial Infarction High Heart Rate Baroreflex Sensitivity Killip Class 
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Copyright information

© Springer-Verlag Italia 2000

Authors and Affiliations

  • F. Hernández-Bernal
    • 1
  • L. Mantini
    • 2
  • R. Latini
    • 1
  • G. Zuanetti
    • 1
  • A. P. Maggioni
    • 1
    • 3
  1. 1.Dipartimento di Ricerche CardiovascolariIstituto Mario NegriMilanItaly
  2. 2.Reparto di CardiologiaOspedale di PenneItaly
  3. 3.Centro Studi ANMCOFlorenceItaly

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