Acute Treatment of Atrial Flutter: Ibutilide, Transesophageal Pacing, or DC Shock?
Drug therapy with class IA and IC antiarrhythmic agents has proven relatively disappointing for the termination of atrial flutter. Unike all other agents, ibutilide, a new pure class III agent, is more effective in patients with atrial flutter than in patients with atrial fibrillation.
KeywordsAtrial Fibrillation Atrial Flutter Electrical Cardioversion Sick Sinus Syndrome Effective Refractory Period
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Ellenbogen KA, Stambler BS, Wodd MA et al (1996) Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and flutter: a dose-response study. J Am Coll Cardiol 28:130–136PubMedCrossRefGoogle Scholar
Stambler BS, Wodd MA, Ellenbogen KA et al (1996) Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation. Circulation 94:1613–1621PubMedCrossRefGoogle Scholar
Murray KT (1998) Ibutilide. Circulation 97:493–497PubMedCrossRefGoogle Scholar
Sotalol Comparator Study (1996) (protocol 0019) Corvert injection (ibutilide fumarate) Comprehensive review. Appendix I. Pharmacia and Upjohn, KalamazooGoogle Scholar
Volgman AS, Stambler BS, Kappagoda C (1996) Comparative efficacy of intravenous Ibutilide versus Procainamide for rapid termination of atrial fibrillation or flutter. Pacing Clin Electrophysiol 9(II):608 (abstr)Google Scholar
Inoue H, Yamashita T, Nozaki A et al (1991) Effects of antiarrhythmic drugs on canine atrial flutter due to reentry: role of prolongation of refractory period and depression of conduction to excitable gap. J Am Coll Cardiol 18:1098–1104PubMedCrossRefGoogle Scholar
Disertori M (1993) La stimolazione atriale transesofagea nel trattamento del flutter atriale: utilità e limiti. G Ital Cardiol 23:281–283PubMedGoogle Scholar
Disertori M, Inama G, Vergara G et al (1984) Impiego della stimolazione atriale transesofagea nel trattamento del flutter atriale. G Ital Cardiol 14:153–159PubMedGoogle Scholar
Guarnerio M, Furlanello F, Del Greco M et al (1989) Transesophageal atrial pacing: a first-choice technique in atrial flutter therapy. Am Heart J 117:1241–1252PubMedCrossRefGoogle Scholar
Doni F, Delia Bella P, Kheir A et al (1995) Atrial flutter termination by overdrive transesophageal pacing and the facilitating effect of oral propafenone. Am J Cardiol 76:1243–1246PubMedCrossRefGoogle Scholar
Stambler BS, Wood MA, Ellenbogen KA (1996) Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by overdrive pacing. Am J Cardiol 77:960–966PubMedCrossRefGoogle Scholar
Olshansky B, Kerber RE (1996) Cardioversion of atrial flutter. In: Waldo AL, Touboul P (eds) Atrial flutter: advances in mechanisms and management. Futura, Armonk NY, pp 366–409Google Scholar
Zarkin GA, Bala MV, Calingaert B et al (1998) The cost-effectiveness of Ibutilide versus electrical cardioversion in the treatment of atrial fibrillation and flutter. Am J Managed Care 22:211–224Google Scholar
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