Advertisement

An Anatomical Approach to Curing Atrial Fibrillation: Pulmonary Vein Isolation with Through-the-Balloon Ultrasound Ablation

  • M. D. Lesh
  • C. Diederich
  • P. Guerra
  • Y. Goseki
  • P. B. Sparks
Conference paper

Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. Drug therapy can be associated with a number of untoward effects, such as proarrhythmia, long-term inefficacy and even an increase in mortality. Catheter ablation of the atrioventricular node with pacemaker implantation [1], or modification of the AV node without pacer implantation [2] can facilitate ventricular rate control, but thromboembolic risk is unchanged and atrial systole is not restored. Given these limitations, an approach that cures atrial fibrillation would be highly desirable.

Keywords

Atrial Fibrillation Pulmonary Vein Catheter Ablation Paroxysmal Atrial Fibrillation Pulmonary Vein Isolation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Langberg JJ, Chin M, Schamp DJ, Lee MA, Goldberger J, Pederson DN, Oeff M, Lesh MD, Griffin JC, Scheinman MM (1991) Ablation of the atrioventricular junction with radiofrequency energy using a new electrode catheter. Am J Cardiol 67:142–147PubMedCrossRefGoogle Scholar
  2. 2.
    Morady F, Hasse C, Strickberger SA, Man KC, Daoud E, Bogun F, Goyal R, Harvey M, Knight BP, Weiss R, Bahu M (1997) Long-term follow-up after radiofrequency modification of the atrioventricular node in patients with atrial fibrillation. J Am Coll Cardiol 29:113–121PubMedCrossRefGoogle Scholar
  3. 3.
    Haissaguerre M, Jais P, Shah DC, Takahashi A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Metayer P, Clementy J (1998) Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339:659–666PubMedCrossRefGoogle Scholar
  4. 4.
    Jais P, Haissaguerre M, Shah D, Chouairi S, Gancel L, Hocini M, Clememty J (1997) A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circulation 95:572–576PubMedCrossRefGoogle Scholar
  5. 5.
    Haissaguerre M, Jais P, Shah D, Lavergne T, Takahashi A, Barold S, Clememty J (1997) Predominant origin of atrial arrhythmia triggers in the pulmonary veins: a distinct electrophysiologic entity. PACE 20(II):1065Google Scholar
  6. 6.
    Nathan H,Eliakim M (1996) The junction between the left atrium and the pulmonary veins. An anatomic study of human hearts. Circulation 34:412–422CrossRefGoogle Scholar
  7. 7.
    Zimmer JE, Hynynen K, He DS, Marcus F (1995) The feasibility of using ultrasound for cardiac ablation. IEEE Trans Biomed Eng 42:891–897PubMedCrossRefGoogle Scholar
  8. 8.
    He DS, Zimmer JE, Hynynen K, Marcus FI, Caruso AC, Lampe LF, Aguirre ML (1995) Application of ultrasound energy for intracardiac ablation of arrhythmias. Eur Heart J 16:961–966Google Scholar
  9. 9.
    Hynynen K, Dennie J, Zimmer JE, Simmons WN, He DS, Marcus FI, Aguirre M (1997) Cylindrical ultrasonic transducers for cardiac catheter ablation. IEEE Trans Biomed Eng 44:144–151PubMedCrossRefGoogle Scholar
  10. 10.
    Robbins IM, Colvin EV, Doyle TP, Kemp WE, Loyd JE, McMahon WS, Kay GN (1998) Pulmonary vein stenosis after catheter ablation of atrial fibrillation. Circulation 98:1769–1775PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2000

Authors and Affiliations

  • M. D. Lesh
    • 1
  • C. Diederich
    • 1
  • P. Guerra
    • 1
  • Y. Goseki
    • 1
  • P. B. Sparks
    • 1
  1. 1.Department of Medicine and the Cardiovascular Research InstituteUniversity of CaliforniaSan FranciscoUSA

Personalised recommendations