Pretreatment with Antiarrhythmic Drugs: Is It Useful to Avoid Immediate and Early Postcardioversion Recurrences?
In patients with atrial fibrillation (AF), restoration of sinus rhythm (SR) may eliminate symptoms and prevent left ventricular dysfunction . Electrical cardioversion is the most effective way to convert persistent AF to SR, since its efficacy is very close to 100% success in the biphasic shock era . Unfortunately, because of the high recurrence rate, particularly in the first few hours after cardioversion, only 30% of patients maintain SR for 6 months or more without antiarrhythmic drug prophylaxis . These findings provide the rationale for pretreatment and long-term prophylaxis with antiarrhythmic agents, although there are some concerns about the risk-benefit ratio of these drugs.
KeywordsAtrial Fibrillation Antiarrhythmic Drug Antiarrhythmic Agent Chronic Atrial Fibrillation Electrical Cardioversion
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