Abstract
The vasovagal or neurally mediated syncope (NMS) is a common disorder of the autonomie cardiovascular regulation, showing a substantial physical and social morbidity. This complex syndrome usually is caused by inappropriate reflex vasodilatation and bradycardia, of sporadic nature. However, a small percentage of patients present NMS as a chronic and recurrent disorder with an important impact on their quality of life. In such circumstances, as NMS becomes a risk for severe trauma, an adequate clinical assessment and careful selection of specific treatment is necessary.
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References
Lacroix D, Kouakam C, Klug D et al (1997) Asystolic cardiac arrest during Head-Up Tilt Test: incidence and therapeutic implications. PACE 20:2746–2754
Moya A, Brignole M, Menozzi C et al (2001) for the ISSUE Investigators. Mechanism of syncope in patients with isolated syncope and in patients with Tilt-positive syncope. Circulation 104:1261–1267
Petersen M, Chamberlain-Webber R, Fitzpatrick A et al (1994) Permanent pacing for cardioinhibitory malignant vasovagal syndrome. Br Heart J 71:274–281
Bendit D, Sutton R, Gammege M et al (1997) Clinical experience with Thera DR Rate-Drop Response pacing algorithm in carotid sinus syndrome and vasovagal syncope. PACE 20:832–839
Shah C, Thakur R, Xei B et al (1999) Dual chamber pacing for neurally mediated syncope with prominent cardioinhibitory component. PACE 22:999–1003
Ammirati F, Colivicchi F, Toscano S et al (1998) DDD pacing with rate drop response function versus DDI with rate hysteresis pacing for cardioinhibitory vasovagal Syncope. PACE 21:2178–2181
Connolly S, Sheldon R, Roberts R et al (1999) The North American Vasovagal Pacemaker Study (VPS). A randomised trial of permanent cardiac pacing for the prevention of vasovagal syncope. J Am Coll Cardiol 33:16–20
Sutton R, Brignole M, Menozzi C et al (2000) for the VASIS Investigators. Dual-Chamber pacing in the treatment of neurally mediated Tilt-Positive cardioinhibitory Syncope. Pacemaker versus no therapy: A multicenter randomised study. Circulation 102:294–299
Ammirati F, Colivicchi F, Santini M et al (2001) for the SYDIT Investigators. Permanent cardiac pacing versus medical treatment for the prevention of recurrent vasovagal syncope. A multicenter, randomized, controlled trial. Circulation 104:52–57
Connolly S, Sheldon R, Thorpe K et al (2003) Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope. JAMA 289:2224–2229
Sheldon R, Rose S, Flanagan P et al (1996) Multivariate predictors of syncope recurrence in drug-free patients following a positive tilt table test. Circulation 93:973–981
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© 2004 Springer-Verlag Italia
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Oseroff, O. (2004). To Pace or Not to Pace for Neurally Mediated Syncope: Do We Know the Answer? A Negative View. In: Raviele, A. (eds) Cardiac Arrhythmias 2003. Springer, Milano. https://doi.org/10.1007/978-88-470-2137-2_86
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DOI: https://doi.org/10.1007/978-88-470-2137-2_86
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2177-8
Online ISBN: 978-88-470-2137-2
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