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To Pace or not to Pace for Neurally Mediated Syncope: Do We Know the Answer? A Positive View

  • F. Giada
  • A. Raviele
Conference paper

Abstract

Single chamber VVI mode pacing proved to be ineffective in vasovagal syncope treatment [1], while several nonrandomized studies [2–4] showed a significant decrease in recurrence in patients who underwent dual chamber pacing. In the last few years, three randomized, noncontrolled studies have shown the efficacy of dual-chamber pacemaker implantation in reducing recurrence in patients with recurrent neuromediated syncope. The VPS study [5] demonstrated the effectiveness of rate-drop response pacemakers in patients affected by neurally mediated syncope who gave a positive response in the tilting test, presenting a varying cardoinhibitory component. The VASIS study [6], on the other hand, showed the effectiveness of a DDI-mode pacemaker with hysteresis in patients with neurally mediated syncope and positive tilting test with a marked cardoinhibitory component. Finally, the SYDIT trial [7] reported the superiority of pacemaker implantation over drug treatment with ß-blockers.

Keywords

Pacemaker Implantation Vasovagal Syncope Syncopic Recurrence Active Pace Implant Loop Recorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • F. Giada
    • 1
  • A. Raviele
    • 1
  1. 1.Cardiovascular DepartmentUmberto I HospitalMestre-VeniceItaly

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