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What Is The Prognostic Value of Non-Sustained Ventricular Tachycardia in Patients Without Severely Depressed Ejection Fraction After Myocardial Infarction?

  • G. Turitto
  • N. El-Sherif
Conference paper

Abstract

Complex Ventricular Ectopy (CVE)/Non-Sustained Ventricular Tachycardia (NS-VT) in the Post-Myocardial Infarction (Ml) Period: Background The predictive accuracy of CVE/NS-VT for serious arrhythmic events/sudden cardiac death (SCD) in the post-MI period has undergone radical evaluation in the last 2 decades. In 1981, Bigger et al reported on 430 patients who sustained acute MI and underwent a 24-hour Holter electrocardiogram (ECG) prior to hospital discharge [1]. Fifty patients (11.6%) had NS-VT, in the form of ≥3 ventricular premature complexes. This group of patients had 38% 1-year mortality rate, compared with a rate of 11.6% in the group without NS-VT. NS-VT had a significant association with many other post-MI risk factors. However, VT was still significantly related to mortality when other variables, including left ventricular ejection fraction (LVEF) were controlled statistically using a multiple logistic regression model. Similar conclusions were later published by Bigger et al. from 820 patients in the Multicenter Post-Infarction Program, of whom 11% had NS-VT recorded on Holter ECG 11±3 days post-MI [2]. NS-VT had a strong and statistically significant association with all-cause and arrhythmic mortality, independent of other risk stratifiers, including depressed LVEF.

Keywords

Heart Rate Variability Left Ventricular Ejection Fraction Sudden Cardiac Death Preserve Left Ventricular Ejection Fraction Postmyocardial Infarction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • G. Turitto
    • 1
  • N. El-Sherif
    • 1
  1. 1.Cardiac Electrophysiology SectionState University of New York, Downstate Medical CenterBrooklynUSA

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