Abstract
Despite very significant advances in the understanding of hypertrophic cardiomyopathy (HCM), the identification of patients at high risk of sudden death remains challenging [1, 2]. The possibility of achieving primary prevention of sudden death following the introduction of the implantable cardioverter-defibrillator in clinical practice has further highlighted the need for reliable indicators of risk. Unfortunately, all markers of risk identified to date have shown a disappointingly low positive predictive value [2].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Maron BJ (2002) Hypertrophic cardiomyopathy: a systematic review. JAMA 287:1308–1320
Elliott PM, Poloniecki J, Dickie S et al (2000) Sudden death in hypertrophic cardiomyopathy: identification of high risk patients. J Am Coll Cardiol 36:2212–2218
Spirito P, Bellone P, Harris KM et al (2000) Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy. N Engl J Med 342:1778–1785
Spirito P, Maron BJ (1990) Relation between extent of left ventricular hypertrophy and occurrence of sudden cardiac death in hypertrophic cardiomyopathy. J Am Coll Cardiol 15:1521–1526
Elliott PM, Gimeno B Jr, Mahon NG et al (2001 ) Relation between severity of left-ventricular hypertrophy and prognosis in patients with hypertrophic cardiomyopathy. Lancet 357:420–424
Maron BJ, Roberts WC, Epstein SE (1982) Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation 65:1388–1394
Louie EK, Maron BJ (1986) Hypertrophic cardiomyopathy with extreme increase in left ventricular wall thickness: functional and morphologic features and clinical significance. J Am Coll Cardiol 8:57–65
Olivotto I, Gistri R, Petrone P et al (2003) Maximum left ventricular thickness and risk of sudden death in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 41:315–321
Olivotto I, Cecchi F, Casey SA et al (2001) Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy. Circulation 104:2517–2524
Maron MS, Olivotto I, Betocchi S et al (2003) Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N Engl J Med 348:295–303
Cecchi F, Olivotto I, Gistri R et al (2001) Coronary microvascular dysnfunction and prognosis in hypertrophic cardiomyopathy. New Engl J Med (in press)
Shirani J, Pick R, Roberts WC, Maron BJ (2000) Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death. J Am Coll Cardiol 35:36–44
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2004 Springer-Verlag Italia
About this paper
Cite this paper
Olivotto, I., Cecchi, F. (2004). Does a Maximum Left Ventricular Thickness Greater than 30 mm Identify Patients with Hypertrophic Cardiomyopathy at Risk of Sudden Death?. In: Raviele, A. (eds) Cardiac Arrhythmias 2003. Springer, Milano. https://doi.org/10.1007/978-88-470-2137-2_49
Download citation
DOI: https://doi.org/10.1007/978-88-470-2137-2_49
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2177-8
Online ISBN: 978-88-470-2137-2
eBook Packages: Springer Book Archive