Rate Control of Atrial Fibrillation: By How Much Should the Ventricular Rate be Lowered?

  • P. Alboni
  • L. Gianfranchi
  • G. Fucà
  • F. Pacchioni
  • G. Corbucci
Conference paper


Heart rate (HR) should be neither too high, since it can be responsible for tachycardia-induced cardiomyopathy [1, 2], nor too low, since it can facilitate the appearance of heart failure, at least in old people with heart disease [3,4], Moreover, mounting evidence shows that an elevated resting sinus rate is a predictor of cardiovascular morbidity and mortality. In fact, in multivariate analysis, a high sinus rate emerged as an independent predictor of mortality in the general population [5], in elderly subjects [6], and in selected groups of patients with hypertension [7] or myocardial infarction [8]. At present the prognostic value of resting HR in patients with chronic atrial fibrillation (AF) is unknown; however, it should be expected to be the same.


Atrial Fibrillation Sinus Rhythm Exercise Capacity Maximal Exercise Chronic Atrial Fibrillation 
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Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • P. Alboni
    • 1
  • L. Gianfranchi
    • 1
  • G. Fucà
    • 1
  • F. Pacchioni
    • 1
  • G. Corbucci
    • 2
  1. 1.Division of Cardiology and Arrhythmologic CenterCento (Fe)Italy
  2. 2.VitatronItaly

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