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Cardiac Arrhythmias 2003 pp 805–813Cite as

How to Identify Patients Most Likely to Respond to Cardiac Resynchronization Therapy

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Abstract

Congestive heart failure (CHF) is one of the major healthy problems in Europe and the United States. It represents the major cause for hospital admission in the adult population with a prevalence from 0.4% up to 2% (22.5 million people world wide and 6.5 million in Europe; 747,000 in Italy). The incidence is 2 million patients per year world wide and 470,000 per year in Europe (66,000 inItaly) [1].

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References

  1. Brown A, Cleland JGF (1998) Influence of concomitant disease on pattern of hospitalisation in patients with heart failure discharged from Scottish hospitals in 1995. Eur Heart J 1063–1069

    Google Scholar 

  2. Cohn JN, Johnson G, Ziesche S et al (1991) A comparison of enalapril with hydralazi-ne-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325:303–310

    Article  PubMed  CAS  Google Scholar 

  3. Captopril Multicenter Research Group (1983) A placebo-controlled trial of captopril in refractory chronic congestive heart failure. J Am Coll Cardiol 2:755–763

    Article  Google Scholar 

  4. Stevenson WG, Stevenson LW, Middlekauff HR et al (1996) Improving survival for patients with atrial fibrillation and advanced heart failure. J Am Coll Cardiol 28:1458–1463

    Article  PubMed  CAS  Google Scholar 

  5. Aaronson KD, Schwartz S, Chen T-M et al (1997) Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation. Circulation 95:2660–2667

    Article  PubMed  CAS  Google Scholar 

  6. Opie LH (1995) Fundamental role of angiotensin-converting enzyme inhibitors in the management of congestive heart failure. Am J Cardiol 75:3F–6F

    Article  PubMed  CAS  Google Scholar 

  7. Packer AC, Gheorghiade M, Young J et al (1993) Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors. N Engl J Med 329:1–7

    Article  PubMed  CAS  Google Scholar 

  8. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators (1993) Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 342:821–828

    Google Scholar 

  9. Cohn JN, Tognoni G, (2001) A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345:16667–16675

    Article  Google Scholar 

  10. Packer M (1998) Do beta-blockers prolong survival in chronic heart failure? A review of the experimental and clinical evidence. Eur Heart J 19 [Suppl B]:B40–46

    Article  PubMed  CAS  Google Scholar 

  11. Packer M, Bristow MR, Cohn JN et al ( 1996) The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 334:1349–1355

    Article  PubMed  CAS  Google Scholar 

  12. Packer M, Coats AJS, Fowler MB et al, for the Carvedilol Prospective Randomized Cumulative Survival Study Group (2001). Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 344:1651–1658

    Article  PubMed  CAS  Google Scholar 

  13. Dargie HJ (2001) Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. Lancet 357:1385–1390

    Article  PubMed  CAS  Google Scholar 

  14. The Resolvd Investigators (2000) Effects of Metoprolol CR in patients with ischemic and dilated cardiomyopathy. The Randomized Evaluation of Strategies for Left Ventricular Dysfunction Pilot Study. Circulation 101:378–384

    Google Scholar 

  15. Goldstein S, Fagerberg B, Hjalmarson A et al, for the MERIT-HF Study Group (2001) Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study. J Am Coll Cardiol 38:932–938

    Article  PubMed  CAS  Google Scholar 

  16. The Beta-Blocker Evaluation of Survival Trial Investigators (2001) Trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med 344:1659–1667

    Article  Google Scholar 

  17. Hochleitner M, Hortnagl H, Ng CK et al ( 1990) Usefulness of physiologic dual-cham-ber pacing in drug-resistant idiopathic dilated cardiomyopathy. Am J Cardiol 66:198–202

    Article  PubMed  CAS  Google Scholar 

  18. Auricchio A, Sommariva L, Salo P et al (1993) Improvement of cardiac function in patients with severe congestive heart failure and coronary artery disease by dual chamber pacing with shortened AV delay. Pacing Clin Electrophysiol 16:2034–2043

    Article  PubMed  CAS  Google Scholar 

  19. Hochleitner M, Hortnagl H et al (1992) Long term efficacy of physiologic dual chamber pacing in the treatment of end stage idiopathic dilated cardiomyopathy. Am J Cardiol 70:1320–1325

    Article  PubMed  CAS  Google Scholar 

  20. Kataoka H (1991) Hemodynamic effect of physiological dual chamber pacing in a patient with end-stage dilated cardiomyopathy: a case report. Pacing Clin Electrophysiol 14:1330–1335

    Article  PubMed  CAS  Google Scholar 

  21. Gold MR, Feliciano Z, Gottlieb SS et al (1995) Dual-chamber pacing with a short atrioventricular delay in congestive heart failure: a randomized study. J Am Coll Cardiol 26:967–973

    Article  PubMed  CAS  Google Scholar 

  22. Linde C, Gadler F, Edner M et al (1995) Results of atrioventricular synchronous pacing with optimized delay in patients with severe congestive heart failure. Am J Cardiol 75:919–923

    Article  PubMed  CAS  Google Scholar 

  23. Brecker SJ, Xiao HB et al (1992) Effects of dual chamber pacing with short AV delay in dilated cardiomyopathy. Lancet 70:1320–1325

    Google Scholar 

  24. Blanc JJ, Etienne Y et al (1997) Evaluation of different ventricular pacing sites in patients with severe heart failure: results of an acute hemodynamic study. Circulation 96:3273–3277

    Article  PubMed  CAS  Google Scholar 

  25. Cazeau S, Ritter P et al (1994) Four chamber pacing in dilated cardiomyopathy. Pacing Clin Electrophysiol 17:1974–1979

    Article  PubMed  CAS  Google Scholar 

  26. Auricchio A, Stellbrink C et al (1999) Pacing therapies for congestive heart failure. (PATH-CHF study). Rational, design and endpoints of a prospective, randomized, multicentric study. Am J Cardiol 83:130–135

    Article  Google Scholar 

  27. Saxon L, Boehemer J, Hummel J (1999) Biventricular pacing in patients with CHF: two prospective randomized trials (Vigor CHF). Am J Cardiol 83:120–123D

    Article  Google Scholar 

  28. Saxon L, Kerwin WF, De Marco T et al (1998) The magnitude of sympathoneural activation in advanced heart failure is altered with chronic biventricular pacing. Arch Mal Coeur Vaiss 91:153

    Google Scholar 

  29. Gras D, Mabo P, Tang T et al (1998) Multisite pacing as a supplemental treatment of CHF: preliminary results of the Medtronic InSync study (NASPE abstr). Pacing Clin Electrophysiol 21:2249–2255

    Article  PubMed  CAS  Google Scholar 

  30. Abraham WT (2001 ) Late breaking clinical trial session at ACC 2001. Am Coll Cardiol 38:604–605

    Google Scholar 

  31. ACC (2002) Late breaking trials. J Am Coll Cardiol 40:13–14

    Google Scholar 

  32. Bristow MR, Feldman AM, Saxon LA, for the COMPANION Steering Committee and COMPANION Clinical Investigators (2000) Heart failure management using implan-table device for ventricular resynchronization: comparison of medical therapy pacing, and defibrillation in chronic heart failure (COMPANION) trial. J Card Fail 6:276–285

    Article  PubMed  CAS  Google Scholar 

  33. Fergusson JJ III (2001) Meeting highlights. Highlights of the XXIII Congress of the European Society of Cardiology. Circulation 104:El11–E116

    Article  Google Scholar 

  34. Medtronic InSync ICD cardiac resynchronization system, www.fda.gov

  35. Huth C, Friedl A, Klein H, Auricchio A (2001) Pacing therapies for congestive heart failure considering the results of the PATH-CHF study. Z Kardiol 90[Suppl 1]:10–15

    Article  PubMed  Google Scholar 

  36. Cazean S, Leclercq C, Lavergne T et al (2001) Effects of multisite biventricular pacing in patients with heart failure and interventricular conduction delay. N Engl J Med 344:873–880

    Article  Google Scholar 

  37. Padeletti L, Porciani MC, Santini M et al (2001) InSync Italian Registry: long term clinical results of cardiac resynchronization. Europace [Suppl 2]:B58:787

    Google Scholar 

  38. Gulizia M, Ricci R, Lunati M et al (2001) InSync Italian Registry: does biventricular pacing impact on patients hospitalizations? Europace [Suppl 2]:B59:816

    Google Scholar 

  39. Auricchio A, Stellbrink C, Sack S et al (2001) PATH-CHF study: reduced hospitaliza-tion days due to heart failure. Europace [Suppl 2]:B49:471

    Google Scholar 

  40. Leclercq C, Cazeau S, Le Breton H et al (1998) Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure. J Am Coll Cardiol 32:1825–1831

    Article  PubMed  CAS  Google Scholar 

  41. Kass DA, Chen CH, Curry C et al (1999) Improved ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay. Circulation 30:1567–1573

    Article  Google Scholar 

  42. Auricchio A, Stellbrink C, Block M et al (1999) Effect of pacing chamber and atrio-ventricular delay on acute systolic function of paced patients with congestive heart failure: the Pacing Therapies for Congestive Heart Failure Study Group: the Guidant Congestive Heart Failure Research Group. Circulation 99:2993–3001

    Article  PubMed  CAS  Google Scholar 

  43. Alonso C, Leclercq C. Victor F et al (1999) Electrocardiographic predictive factors of long-term clinical improvement with multisite biventricular pacing in advanced heart failure. Am J Cardiol 84:1417–1421

    Article  PubMed  CAS  Google Scholar 

  44. Kadhiresan V, Vogt J, Auricchio A et al (2000) Sensitivity and specificity of QRS duration to predict acute benefit in heart failure patients with cardiac resynchronization. NASPE 11:555

    Google Scholar 

  45. Nelson G, Curry CW, Wyman BT et al (2000) Predictors of systolic augmentation from left ventricular preexcitation in patients with dilated cardiomyopathy and intra-ventricular conduction delay. Circulation 101:2703–2709

    Article  PubMed  CAS  Google Scholar 

  46. Butter C, Auricchio A, Stellbrink C et al (2001) Longer LV-RV delay may not yield better BiVRT outcome in HF. Europace [Suppl 2]:B11:649

    Google Scholar 

  47. Yu Y, Auricchio A, Butter C et al (2001) Assess effectiveness of BiVRT using surface QRS duration. Europace [Suppl 2] B11:770

    Google Scholar 

  48. Achilli A, Bocchiardo M, Sassara M et al (2001) Biventricular stimulation: comparison of results of sinus rhythm and chronic atrial fibrillation patients. Europace [Suppl 2]:B11:612

    Google Scholar 

  49. Montenero AS, Santini M, Lunati M et al (2001) InSync Italian Registry: baseline predictive factors of the clinical outcome. Europace [Suppl 2]:B49:613

    Google Scholar 

  50. Breithardt OA, Stellbrink C, Franke A, Balta O, Diem BH, Bakker P, Sack S, Auricchio A, for the PATH-CHF Study Group, and Pochet T, Salo R, for the Guidant Congestive Heart Failure Research (2002) Acute effects of cardiac resynchronization therapy on left ventricular Doppler indices in patients with congestive heart failure. Am Heart J 143:34–44

    Article  PubMed  Google Scholar 

  51. Sogaard P, Kim WY, Jensen HK, Mortensen P, Pedersen AK, Kristensen BO, Egeblad H (2001) Impact of acute biventricular pacing on left ventricular performance and volumes in patients with severe heart failure: a tissue Doppler and three-dimensional echocardiographic study. Cardiology 95:173–182

    Article  PubMed  CAS  Google Scholar 

  52. Cazeau S, Gras D, Lazarus A, Ritter P, Mugica J (2000) Multisite stimulation for correction of cardiac asynchrony. Heart 84:579–581

    Article  PubMed  CAS  Google Scholar 

  53. Yu CM, Chau E, Sanderson JE, Fan K, Tang MO, Fung WH, Lin H, Kong SL, Lam YM, Hill MRS, Lau CP (2002) Tissue Doppler echocardiographic evidence of reverse

    Google Scholar 

  54. Gras D, Cebron JP, Brunei P, Leurent B, Bonus Y (2003) Selection of patients for cardiac resynchronization therapy. In: Gulizia M (ed) New Advances in Heart Failure and Atrial Fibrillation. Proceedings of the Mediterranean Cardiology Meeting. Springer-Verlag Italia, Milan, pp 237–241

    Google Scholar 

  55. Cleland JGF, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, Klein W, Tavazzi L, on behalf of the CARE-HF study steering committee and investigators (2001) The CARE-HF study (Cardiac Resynchronisation in Heart Failure study): rationale, design and end-points. Eur J Heart Fail 3:481–489

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Cardiologia, Ospedale “S. Luigi-S. Currò”, Catania, Italy

    M. M. Gulizia & G. M. Francese

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  1. M. M. Gulizia
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  2. G. M. Francese
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Editors and Affiliations

  1. Divisione di Cardiologia, Ospedale Umberto I, Via Circonvallazione 50, I-30174, Venezia, Mestre, Italy

    Antonio Raviele MD

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Gulizia, M.M., Francese, G.M. (2004). How to Identify Patients Most Likely to Respond to Cardiac Resynchronization Therapy. In: Raviele, A. (eds) Cardiac Arrhythmias 2003. Springer, Milano. https://doi.org/10.1007/978-88-470-2137-2_107

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  • DOI: https://doi.org/10.1007/978-88-470-2137-2_107

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2177-8

  • Online ISBN: 978-88-470-2137-2

  • eBook Packages: Springer Book Archive

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