Cardiac Resynchronization Therapy: What Are the Benefits of Digital Pacemakers?

  • G. Fröhlig
  • P. Wohlgemuth
  • N. M. Van Hemel
  • A. Vincent
Conference paper


While many applications in daily life switched from analogue to digital techniques long ago, pacemakers are only just entering the field of digital signal processing (DSP). Possible reasons for the late implementation of DSP are the widespread satisfaction with the technology already available and the difficult balance between calculating plus storing capacity and the energy constraints of small batteries. DSP, however, offers basic advantages that may also improve the performance of pacemakers.


Cardiac Resynchronization Therapy Digital Signal Processing Atrial Electrogram Dual Chamber Pace Digital Signal Processing System 
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  1. 1.
    Fröhlig G, Kindermann M, Seikat N, Wallbrück K, Böhm M, Schaldach M (2001 ) What pacemaker sense filters do discriminate best between P and far field R signals from atrial leads with different design? Pacing Clin Electrophysiol 24:663Google Scholar
  2. 2.
    Brouwer J, Nagelkerke D, den Heijer P, Ruiter JH, Mulder H, Begemann M], Lie KI (1997) Analysis of atrial sensed far-field ventricular signals: a reassessment. Pacing Clin Electrophysiol 20:916–922PubMedCrossRefGoogle Scholar
  3. 3.
    Fröhlig G, Helwani Z, Kusch O, Berg M, Schieffer H (1999) Bipolar ventricular far-field signals in the atrium. Pacing Clin Electrophysiol 22:1604–1613PubMedCrossRefGoogle Scholar
  4. 4.
    Throne RD, Jenkins JM, Winston SA, Finelli CJ, Di Carlo LA (1989) Discrimination of retrograde from anterograde atrial activation using intracardiac electrogram waveform analysis. Pacing Clin Electrophysiol 12:1622–1630PubMedCrossRefGoogle Scholar
  5. 5.
    Sun W, Combs W, Panken E, Fotuhi P, Stangl K, Baumann G, Theres H (1999) Automatic and efficient R wave discrimination in the right atrium using a two-state hidden Markov model. J Cardiovasc Electrophysiol 10:343–350PubMedCrossRefGoogle Scholar
  6. 6.
    Chiang CM, Jenkins JM, DiCarlo LA (1994) Digital signal processing chip implementation for detection and analysis of intracardiac electrograms. Pacing Clin Electrophysiol 17:1373–1379PubMedCrossRefGoogle Scholar
  7. 7.
    Theres H, Sun W, Combs W, Panken E, Mead H, Baumann G, Stangl K (2000) P wave and far-field R wave detection in pacemaker patient atrial electrograms. Pacing Clin Electrophysiol 23:434–440PubMedCrossRefGoogle Scholar
  8. 8.
    Van Hemel NM, Wohlgemuth P, Munnike D, Westendorp H, Engbers JG, Lawo T, Nebaznivy J, Taborsky M, Witte J (2003) Far field R wave discrimination by means of form analysis of atrial events. Pacing Clin Electrophysiol 26:930Google Scholar
  9. 9.
    Linde C, Markewitz A, Strandberg H, Larsson B, Binner L, Schuller H (2001) Combipolar sensing in dual chamber pacing: is there still a need for bipolar leads in the atrium? Pacing Clin Electrophysiol 24:1664–1671PubMedCrossRefGoogle Scholar
  10. 10.
    Hexamer MP, Meine M, Kloppe A, Werner J (2002) Rate-responsive pacing based on the atrio-ventricular conduction time. IEEE Trans Biomed Eng 49:185–195PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • G. Fröhlig
    • 1
  • P. Wohlgemuth
    • 2
  • N. M. Van Hemel
    • 3
  • A. Vincent
    • 2
  1. 1.Medizinische UniversitätsklinikInnere Medizin IIIHomburgGermany
  2. 2.Vitatron B.V.ArnhemThe Netherlands
  3. 3.St. Antonius HospitalNieuwegeinThe Netherlands

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