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Intravascular Catheter- Related Infections: An Update on Epidemiology and Prevention

  • M. Viviani
  • R. Dezzoni
  • L. Silvestri
  • H. K. F. van Saene

Abstract

In modern-day medical care, the use of intravascular devices, especially in an intensive care (ICU) setting, is necessary because of the continuous increase in the numbers of catheters inserted, the possibility to administer various fluids and the use of invasive cardiovascular monitoring. However, extensive clinical use of central venous catheters (CVC) is associated with various iatrogenic diseases, particularly local and systemic infectious complications, such as local site infections, intravascular catheter-related bloodstream infections (CR-BSI), septic thrombophlebitis, endocarditis and metastatic infections (e.g., cerebral abscess, lung abscess, osteomyelitis).

Keywords

Central Venous Catheter Intravascular Catheter National Nosocomial Infection Surveillance Intravascular Device Catheter Surface 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Polderman KH, Girbes ARJ (2002) Central venous catheter use. Part 2: infectious complications. Intensive Care Med 28:18–28Google Scholar
  2. 2.
    (2002) Guidelines for the Prevention of Intravascular Catheter-Related Infections. MMWR. CDC 51(RR-10):1–30Google Scholar
  3. 3.
    CDC (1999) National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990-May 1999, issue June 1999. Am J Infection Control 27:520–532Google Scholar
  4. 4.
    CDC (2001) National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1992-June 2001. Am J Infection Control 6:404–421Google Scholar
  5. 5.
    Pearson ML (1996) Hospital Infection Control Practices Advisory Committee. Guideline for Prevention of Intravascular device-related Infections. Infect Control Hosp Epidemiol 17:438–473Google Scholar
  6. 6.
    Crnich CJ, Maki DG (2002) The promise of novel technology for the prevention of intravascular device-related bloodstream infections. Pathogenesis and short-term devices. Clin Infect Dis 34:1232–1242Google Scholar
  7. 7.
    Kluger DM, Maki DG (1999) The relative risk of intravascular device related blood-stream infections in adults (abstract). In: Abstract of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA: American Society for Microbiology, pp 514Google Scholar
  8. 8.
    Schaberg DR, Culver DH, Gaynes RP (1991) Major trends in the microbial etiology of nosocomial infection. Am J Med 91(Suppl) S72–S75Google Scholar
  9. 9.
    Sheth NK, Franson TR, Rose HD et al (1983) Colonization of bacteria on polyvinyl chloride and Teflon intravascular catheters in hospitalized patients. J Clin Microbiol 18:1061–1063PubMedCentralPubMedGoogle Scholar
  10. 10.
    Nachnani GH, Lessin LS, Motomiya T et al (1972) Scanning electron microscopy of thrombogenesis on vascular catheter surface. N Engl J Med 286:139–140PubMedCrossRefGoogle Scholar
  11. 11.
    Herrmann M, Lai QJ, Albrecht RM et al (1993) Adhesion of Staphylococcus aureus to surface-bound platelets: a role of fibrinogen/fibrin and platelet integrins. J Infect Dis 167:312–322PubMedCrossRefGoogle Scholar
  12. 12.
    Raad I (1998) Intravascular-catheter-related infections. Lancet 351:893–898PubMedCrossRefGoogle Scholar
  13. 13.
    Branchini ML, Pfaller MA, Rhine-Chalberg J et al (1994) Genotypic variation and slime production among blood and catheter isolates of Candida Parapsilosis. J Clin Micrl 32:452–456Google Scholar
  14. 14.
    Maki DG, Ringer M (1987) Evaluation of dressing regimens for prevention of infection with peripheral intravenous catheters: gauze, a trasparent polyurethane dressing, and iodophor-trasparent dressing. JAMA 258:2396–2403PubMedCrossRefGoogle Scholar
  15. 15.
    Maki DG, Ringer M (1991) Risk factors for infusion-related phlebitis with small peripheral venous catheters: a randomized controlled trial. Ann Intern Med 114:845–854PubMedCrossRefGoogle Scholar
  16. 16.
    Tebbs SE, Sawyer A, Elliot TSJ (1994) Influence of surface morphology on in vitro bacterial adherence to central venous catheters. Br J Anaesth 72:587–591PubMedCrossRefGoogle Scholar
  17. 17.
    Gil RT, Kruse JA, Thill-Baharozian MC, Carolson RW (1989) Triple-vs single-lumen central venous catheters. A prospective study in a critically ill population. Arch Int Med 149:1139–1143Google Scholar
  18. 18.
    (2001) Guidelines for preventing infections associated with the insertion and maintenance of central venous catheters. J Hosp Infection 47(Suppl.):S47–S67Google Scholar
  19. 19.
    Clark-Christoff N, Waiters VA, Sparks W et al (1992) Use of triple-lumen subclavian catheters for administration of total parenteral nutrition. J Parent Enterai Nutrit 16:403–407CrossRefGoogle Scholar
  20. 20.
    Andrivet P, Bacquer A, Ngoc CV et al (1994) Lack of clinical benefit from subcutaneous tunnel insertion of central venous catheters in immunocompromised patients. Clin Inf Dis 18:199–206CrossRefGoogle Scholar
  21. 21.
    Randolph A, Cook D, Gonzales C et al (1998) Tunnelling short-term central venous catheters to prevent catheter-related infection: a meta-analysis of randomized controlled trials. Crit Care Med 26:1452–1457PubMedGoogle Scholar
  22. 22.
    Richet H, Hubert B, Nitenberg G et al (1990) Prospective multicenter study of vascular catheter related complications and risk factors for positive central catheter cultures in intensive care unit patients. J Clin Microbiol 28:2520–2525PubMedCentralPubMedGoogle Scholar
  23. 23.
    Mermel LA, McCormick RD, Springman SR et al (1991) The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: a prospective study utilizing molecular subtyping. Am J Med 91(Suppl 3B)197S–205SGoogle Scholar
  24. 24.
    Fletcher SJ, Bodenham AR (1999) Catheter-related sepsis: an overview-Part 1. Br J Int Care 9:46–53Google Scholar
  25. 25.
    Trottier SJ, Veremakis C, O’Brien J et al (1995) Femoral deep vein thrombosis associated with central venous catherisation: results from a prospective, randomized trial. Crit Care Med 23:52–59PubMedGoogle Scholar
  26. 26.
    Ryder MA (1995) Peripheral access options. Surg Oncol Clin North Am 4:395–427Google Scholar
  27. 27.
    Maki DG, Ringer M, Alvarado CJ (1991) Prospective randomized trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet 338:339–343PubMedCrossRefGoogle Scholar
  28. 28.
    Maki DG, Knasinski V, Narans LL et al (2001) A randomized trial of a novel 1% chlorhexidine-75% alcohol tincture versus 10% povidone-iodine for cutaneous disinfection with vascular catheters (abstract 142). In: Program and abstracts of the 31st Annual Society for Hospital Epidemiology of America Meeting (Toronto). Thorofare, NJ: Society for Hospital Epidemiology of America: 70Google Scholar
  29. 29.
    Mimoz O, Pieroni L, Lawrence C et al (1996) Prospective, randomized trial of two antiseptic solutions for prevention of central venous and arterial catheter colonization and infection in intensive care unit patients. Crit Care Med 24:1818–1823PubMedGoogle Scholar
  30. 30.
    Flowers RHD, Schwenzer KJ, Kopel RF et al (1989) Efficacy of an attachable subcutaneous cuff for the prevention of intravascular catheter-related infection: a randomized, controlled trial. JAMA 261:878–883PubMedCrossRefGoogle Scholar
  31. 31.
    Maki D, Will L (1986) Study of polyantibiotic and povidone-iodine ointments on central venous and arterial catheter sites dressed with gauze or polyurethane dressing (abstract). In program and abstracts of the 26th interscience conference on antimicrobial agents and chemotherapy (New Orleans). Washington, DC: American Society for Microbiology: 311Google Scholar
  32. 32.
    Prager RL, Silva J (1984) Colonization of central venous catheters. South Med J 77:458–461PubMedCrossRefGoogle Scholar
  33. 33.
    Levin A, Mason AJ, Jindal KK et al (1991) Prevention of haemodialysis subclvian vein catheter infections by topical povidone-iodine. Kidney Int 40:934–938PubMedCrossRefGoogle Scholar
  34. 34.
    Hill RL, Fisher AP, Ware RJ et al (1990) Mupirocin for the reduction of colonization of internal jugular cannulae-a randomized controlled trial. J Hosp Infect 15:311–321PubMedCrossRefGoogle Scholar
  35. 35.
    Sesso R, Barbosa D, Leme IL et al (1998) Staphylococcus aureus prophylaxis in hemodialysis patients using central venous catheter: effect of mupirocin ointment. J Am Soc Nephrol 9:1085–1092PubMedGoogle Scholar
  36. 36.
    Zakrzewska-Bode A, Muytjens HL, Liem HD et al (1995) Mupirocin resistance in coagulase-negative staphylococci, after topical prophylaxis for the reduction of colonization of central venous catheters. J Hosp Infect 31:189–193PubMedCrossRefGoogle Scholar
  37. 37.
    Miller MA, Dascal A, Portnoy J et al (1996) Development of mupirocin resistance among methicillin-resistant Staphylococcus aureus after widespread use of nasal mupirocin ointment. Infect Control Hosp Epidemiol 17:811–813PubMedCrossRefGoogle Scholar
  38. 38.
    Carratalà J, Niubò J, Fernandez-Sevilla A et al (1999) Randomized, double-blind trial of an antibiotic-lock techinique for prevention of Gram-positive central venous catheter related infection in neutropenic patients with cancer. Antimicrob Agents Chemother 43:2200–2204PubMedCentralPubMedGoogle Scholar
  39. 39.
    Henrickson KJ, Axtell RA, Hoover SM et al (2000) Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: a randomised, multicenter, double-blind trial. J Clin Oncol 1269–1278Google Scholar
  40. 40.
    Maki DG, Stolz SM, Wheeler SJ et al (1992) A prospective, randomized, three-way clinical comparison of a novel highly permeable polyurethane dressing with 442 Swan-Ganz catheter (abstract 825). In program and abstract 32nd interscience conference on antimicrobial agents and chemotherapy (Anaheim). Washington DC: American Society for Microbiology: 248Google Scholar
  41. 41.
    Wille JC, Blusse van Oud Albas A, Thewessen EA (1993) A comparison of two transparent film-type dressings in central venous therapy. J Hosp Infect 23:113–121PubMedCrossRefGoogle Scholar
  42. 42.
    Maki DG, Mermel LA, Kluger DM et al (2000) The efficacy of a chlorhexidine-impregnated sponge (biopatch) for the prevention of intravascular catheter-related infection-a prospective, randomized, controlled, multicenter trial (abstract 1430). In program and abstract 40th interscience conference on antimicrobial agents and chemotherapy (Toronto). Washington DC: American Society for Microbiology: 422Google Scholar
  43. 43.
    Cobb DK, High K, Sawyer RG et al (1992) A controlled trial of scheduled replacement of central venous and pulmonary artery catheters. New Engl J Med 327:1062–1068PubMedCrossRefGoogle Scholar
  44. 44.
    Snyder RH, Archer FJ, Endi T et al (1988) Catheter infection: a comparison of two catheter maintainance techniques. Ann Surg 208:651–653PubMedCentralPubMedCrossRefGoogle Scholar
  45. 45.
    Mermel LA (2000) Prevention of intravascular catheter related infections. Ann Intern Med 132:391–402PubMedCrossRefGoogle Scholar
  46. 46.
    Veenstra DL, Saint S, Saha S et al (1999) Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection: a meta-analysis. JAMA 281:261–267PubMedCrossRefGoogle Scholar
  47. 47.
    Darouiche RO, Raad II, Heard SO et al (1999) A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group. N Engl J Med 340:1–8CrossRefGoogle Scholar
  48. 48.
    McConnel SA, Gubbins PO, Anaissie EJ (2003) Do antimicrobial-impregnated central venous catheters prevent catheter-related bloodstream infection? Clin Infect Dis 37:65–72CrossRefGoogle Scholar
  49. 49.
    Schierholz JM, Lucas LJ, Rump A et al (1998) Efficacy of Silver-coated medical devices. J Hosp Infec 40:257–262CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • M. Viviani
  • R. Dezzoni
  • L. Silvestri
  • H. K. F. van Saene

There are no affiliations available

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