Abstract
Many diseases result in degeneration of the nervous system. To name a few: infection, multiple sclerosis, and tumors destroy neuronal tissue. However, the term neurodegenerative disorders refers to a group of diseases that share the characteristic of death of subsets of specific classes of neurons. Another common feature of the class of neurodegenerative disorders is the fact that they are idiopathic, the etiology of these diseases is not completely understood. With increasing knowledge of the pathogenesis of these diseases, disorders that are presently classified as neurodegenerative will be grouped among diseases with a known pathogenesis, and consequently, the list of degenerative disorders will decrease. This paper discusses the neuroradiological aspects of a number of disorders that are presently considered to be neurodegenerative.
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Aoki S, Okada Y, Nishimura K et al (1989) Normal deposition of brain iron in childhood and adolescence: MR imaging at 1.5 T. Radiology 172:381–385
Bryan RN, Wells SW, Miller TJ et al (1997) Infarctlike lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly — data from the Cardiovascular Health Study. Radiology 202:47–54
Caplan LR (1995) Binswanger’s disease — revisited. Neurology 45:626–633
Drayer BP (1988) Imaging of the aging brain. Part I. Normal findings. Radiology 166:785–796
Drayer BP (1988) Imaging of the aging brain. Part IL Pathologic conditions. Radiology 166:797–806
Esiri MM, Hyman BT, Beyreuther K, Masters CL (1997) Ageing and dementia. In: Graham DI, Lantos PL (eds) Greenfield’s neuropathology, vol. 2. Arnold, London, pp 153–233
Grossman RI, Yousem DM (2003) Neuroradiology — the requisites, 2nd edn. Mosby, St. Louis.
Guttmann CRG, Jolesz FA, Kikinis R et al (1998) White matter changes with normal aging. Neurology 50:972–978
Jack CR, Lexa FJ, Trojanowski JQ, Braffman BH, Atlas SW (2003) Normal aging, dementia, and neurodegenerative disease. In: Atlas SW (ed) Magnetic resonance imaging of the brain and spine, 3rd edn. Lippincott Williams Wilkins, Philadelphia, pp 1177–1240
Lechner H, Schmidt R, Fazekas F et al (1994) White matter lesions on magnetic resonance imaging in a healthy elderly population: correlations to vascular risk factors and carotid atherosclerosis. J Stroke Cerebrovasc Dis 4:224–228
Milton WJ, Atlas SW, Lexa FJ, Mozley PD, Gur RE (1991) Deep gray matter hypointensity patterns with aging in healthy adults: MR imaging at 1.5 T. Radiology 181:715–719
Nagata K, Basugi N, Fukushima T et al (1987) A quantitative study of physiological cerebral atrophy with aging: a statistical analysis of the normal range. Neuroradiology 29:327–332
Pantoni L, Garcia JH (1995) The significance of cerebral white matter abnormalities 100 years after Binswanger’s report — a review. Stroke 26:1293–1301
Roman GC (1996) From UBOs to Binswanger’s disease — impact of MRI on vascular dementia research. Stroke 27:1269–1273
Roman GC, Tatemichi TK, Erkinjuntti T et al (1993) Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43:250–260
Rowe JW, Kahn RL (1987) Human aging: usual and successful. Science 237:143–149
Valk J, Barkhof F, Scheltens P (2002) Magnetic resonance in dementia. Springer, Berlin Heidelberg New York
Ylikoski A, Erkinjuntti T, Raininko R, Sarna S, Sulkava R, Tilvis R (1995) White matter hyperintensities on MRI in the neurologically nondiseased elderly — analysis of cohorts of consecutive subjects aged 55 to 85 years living at home. Stroke 26:1171–1177
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© 2004 Springer-Verlag Italia
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van Buchem, M.A. (2004). Brain Degeneration and Aging. In: von Schulthess, G.K., Zollikofer, C.L. (eds) Diseases of the Brain, Head and Neck, Spine. Springer, Milano. https://doi.org/10.1007/978-88-470-2131-0_9
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DOI: https://doi.org/10.1007/978-88-470-2131-0_9
Publisher Name: Springer, Milano
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