Skip to main content

Spinal Inflammation and Demyelinating Diseases

  • Chapter
Diseases of the Brain, Head and Neck, Spine
  • 386 Accesses

Abstract

Clinical presentation and imaging findings of spinal inflammatory and demyelinating diseases are protean and often non-specific. They may mimic neoplastic lesions either clinically or radiologically. Magnetic resonance imaging (MRI) is the best imaging modality to screen patients who are clinically suspected of having myelitis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Plum F, Olson ME (1973) Myelitis and myelopathy. In: Baker AB, Baker LH (eds) Clinical neurology. Harper Row, Hagerstown, pp 1–52

    Google Scholar 

  2. Manelfe C (1992) Imaging of the spine and spinal cord. Raven, New York

    Google Scholar 

  3. Dietemann JL, Thibaut-Menard A, Warter JM et al (2000) MRI in multiple sclerosis of the spinal cord: evaluation of fast short inversion-recovery and spin-echo sequences. Neuroradiology 42:810–813

    Article  PubMed  CAS  Google Scholar 

  4. Finelli DA, Ross JS (2000) MR imaging of intrinsic inflammatory myelopathies. Magn Reson Imaging Clin N Am 8:541–560

    PubMed  CAS  Google Scholar 

  5. Pattany PM, Puckett WR, Klose KJ et al (1997) High resolution diffusion-weighted MR of fresh and fixed cat spinal cords: evaluation of diffusion coefficients and anisotropy. AJNR Am JNeuroradiol 18:1049–1056

    CAS  Google Scholar 

  6. Balériaux D, Parizel P, Bank WO (1992) Intraspinal and intramedullary pathology. In: Manelfe C (ed) Imaging of the spine and spinal cord. Raven, New York, pp 513–564

    Google Scholar 

  7. Tartaglino LM, Friedman DP, Flanders AE et al (1995) Multiple sclerosis in the spinal cord: MR appearance and correlation with clinical parameters. Radiology 195:725–732

    PubMed  CAS  Google Scholar 

  8. Thielen KR, Miller GM (1996) Multiple sclerosis of the spinal cord: magnetic resonance appearance. J Comput Assist Tomogr 20:434–438

    Article  PubMed  CAS  Google Scholar 

  9. Tartaglino LM, Croul SE, Flanders AE, Sweeney JD, Schwartzmann RJ, Liem M (1996) Idiopathic acute transverse myelitis: MR imaging findings. Radiology 201:661–669

    PubMed  CAS  Google Scholar 

  10. Lyclama A Nijeholft GJ, Barkhof F, Scheltens P et al (1997) MR of the spinal cord in multiple sclerosis: relation to clinical subtype and disability. AJNR Am J Neuroradiol 18:1041–1048

    Google Scholar 

  11. Silver NC, Barker GJ, Losseff NA et al (1997) Magnetization transfer ratio measurements in the cervical spinal cord: a preliminary study in multiple sclerosis. Neuroradiology 39:441–445

    Article  PubMed  CAS  Google Scholar 

  12. Kesserling J, Miller DH, Robb SA, Kendall BE, Moseley IF, Kingsley D, Du Boulay EPGH, McDonald WI (1990) Acute disseminated encephalomyelitis: MRI findings and the distinction from multiple sclerosis. Brain 113:291–302

    Article  Google Scholar 

  13. Caldemeyer KS, Smith RR, Harris TM, Edwards MK (1994) MRI in acute disseminated encephalomyelitis. Neuroradiology 36:216–220

    Article  PubMed  CAS  Google Scholar 

  14. Junger SS, Stern BJ, Levine SR, Sipos E, Marti-Masso F (1993) Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics. Neurology 43:333–337

    Article  PubMed  CAS  Google Scholar 

  15. Mantienne C, Albucher JF, Catalaâ I, Sévely A, Cognard C, Manelfe C (2001) MRI in Lyme disease of the spinal cord. Neuroradiology 43:485–488

    Article  PubMed  CAS  Google Scholar 

  16. Byrne TN, Benzel EC, Wasman SG (2000) Diseases of the spine and spinal cord. Oxford University, Oxford, pp 266–313

    Google Scholar 

  17. Choi KH, Lee KS, Chung So et al (1996) Idiopathic transverse myelitis: MR characteristics. AJNR Am J Neuroradiol 20:1412–1416

    Google Scholar 

  18. Barakos JA, Mark AS, Dillon WP, Norman D (1990) MR imaging of acute transverse myelitis and AIDS myelopathy. J Comput Assist Tomogr 14:45–50

    Article  PubMed  CAS  Google Scholar 

  19. Petito CK (1997) The neuropathology of human immunodeficiency virus infection in the spinal cord. In: Berger JR, Levy RM (eds) AIDS and the nervous system, 2nd edn. Lippincott-Raven, Philadelphia, pp 451–459

    Google Scholar 

  20. Quencer RM, Post MJD (1997) Spinal cord lesions in patients with AIDS. Neuroimaging Clin N Am 7:359–373

    PubMed  CAS  Google Scholar 

  21. Santosh CG, Bell JE, Best JJK (1995) Spinal tract pathology in AIDS: postmortem MRI correlation with neuropathology. Neuroradiology 3:134–138

    Article  Google Scholar 

  22. Turnher MM, Post MJD, Jinkins JR (2000) MRI of infections and neoplasms of the spine and spinal cord in 55 patients with AIDS. Neuroradiology 42:551–563

    Article  Google Scholar 

  23. Vernant JC, Maurs L, Gessain A et al (1987) Endemic tropical spastic paraparesis associated with human T-lymphotropic virus type 1: a clinical and seroepidemiological study of 25 cases. Ann Neurol 21:123–130

    Article  PubMed  CAS  Google Scholar 

  24. Shakudo M, Inoue Y, Tsutada T (1999) HTLV-1 associated myelopathy: acute progression and atypical MR findings. AJNR Am J Neuroradiol 20:1417–1421

    PubMed  CAS  Google Scholar 

  25. D’Angelo CM, Whisler W (1978) Bacterial infections of the spinal cord and its coverings. In: Vinken PJ, Bruyn GW (eds) Handbook of Clinical Neurology, vol. 33. Infections of the Nervous System, part I. North-Holland, Amsterdam, pp 187–194

    Google Scholar 

  26. Sverzut JM, Laval C, Smadja P, Gigaud M, Sevely A, Manelfe C (1998) Spinal cord abscess in a heroin addict: case report. Neuroradiology 40:455–458

    Article  PubMed  CAS  Google Scholar 

  27. Timms SR, Cure JK, Kurent JE (1993) Subacute combined degeneration of the spinal cord: MR findings. AJNR Am J Neuroradiol 14:1224–1227

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Springer-Verlag Italia

About this chapter

Cite this chapter

Manelfe, C. (2004). Spinal Inflammation and Demyelinating Diseases. In: von Schulthess, G.K., Zollikofer, C.L. (eds) Diseases of the Brain, Head and Neck, Spine. Springer, Milano. https://doi.org/10.1007/978-88-470-2131-0_31

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2131-0_31

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0251-7

  • Online ISBN: 978-88-470-2131-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics