Degenerative Diseases of the Spine

  • B. C. Bowen


The intervertebral disk consists of three components: cartilaginous endplate (hyaline cartilage), nucleus pulposus (fibrocartilage with ground substance containing hyaluronic acid and glycosaminoglycans), and anulus fibrosus (inner part contains fibrocartilage, while the outer part has dense fibrous lamellae with fibers, called Sharpey fibers, that insert on the vertebral ring apophysis). The inner part of the anulus and the nucleus pulposis are indistinguishable on magnetic resonance imaging (MRI). In the normal adult disk, a hypointense band or cleft is observed at the center of the nucleus pulposus and inner anulus on T2-weighted sagittal images and has been attributed to a higher concentration of collagen in this region of the disk. The adult disk normally lacks innervation and vascularity.


Nucleus Pulposus Disk Herniation Lumbar Spinal Stenosis Ligamentum Flavum Foraminal Stenosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Bowen BC (2001) Spine imaging: case review. Mosby, PhiladelphiaGoogle Scholar
  2. 2.
    Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N (2001) Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine 26:1873–1878PubMedCrossRefGoogle Scholar
  3. 3.
    Tanaka N, An HS, Lim TH, Fujiwara A, Jeon CH, Haughton VM (2001) The relationship between disc degeneration and flexibility of the lumbar spine. Spine J 1:47–56PubMedCrossRefGoogle Scholar
  4. 4.
    Czervionke LF, Haughton VM (2002) Degenerative disease of the spine. In: Atlas SW (ed) Magnetic resonance imaging of the brain and spine, 3rd edn. Lippincott Williams Wilkins, Philadelphia, pp 1633–1713Google Scholar
  5. 5.
    Fardon DE, Milette PC (2001) Nomenclature and classification of lumbar disc pathology: recommendations of the combined task forces of the North American Spine Society, American Society of Spine Radiology, and American Society of Neuroradiology. Spine 26:E93–E113PubMedCrossRefGoogle Scholar
  6. 6.
    Schellinger D, Manz HJ, Vidic B, Patronas NJ, Deveikis JP, Muraki AS, Abdullah DC (1990) Disk fragment migration. Radiology 175:831–836PubMedGoogle Scholar
  7. 7.
    Lane JI, Koeller KK, Atkinson LD (1994) Enhanced lumbar nerve roots in the spine without prior surgery: radiculitis or radicular veins? AJNR Am J Neuroradiol 15:1317–1325PubMedGoogle Scholar
  8. 8.
    Wagner AL, Murtagh FR, Arlington JA, Stallworth D (2000) Relationship of Schmorl’s nodes to vertebral body endplate fractures and acute endplate disk extrusions. AJNR Am J Neuroradiol 21:276–281PubMedGoogle Scholar
  9. 9.
    Lee TT, Manzano GR, Green BA (1997) Modified open-door cervical expansive laminoplasty for spondylotic myelopathy: operative technique, outcome, and predictors for gait improvement. J Neurosurg 86:64–68PubMedCrossRefGoogle Scholar
  10. 10.
    Ross JS (1999) MR imaging of the postoperative lumbar spine. Magn Reson Imaging Clin N Am 7:513–524PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • B. C. Bowen
    • 1
  1. 1.Neuroradiology Section, MRI Center, Department of RadiologyUniversity of Miami School of MedicineMiamiUSA

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