Imaging the Patient with Seizures

  • P. Ruggieri
  • A. Nusbaum


Seizures occur as a result of excessive, prolonged and synchronous electrical discharges of neurons within the brain parenchyma that alter neurologic function. Seizures may be acute or provoked such as in the case of a patient with a recent closed head injury, acute intracranial inflammatory process, or an acute cerebral infarct. The term “epilepsy” is applied to chronic, recurrent seizures. These seizures may be partial or focal in onset from a certain region of the brain such as the parenchyma adjacent to a neoplasm. Alternatively, the seizures may be generalized with simultaneous onset of the abnormal electrical activity from both cerebral hemispheres. If the data are insufficient to make these distinctions, the seizures are listed as unclassified. There is a higher incidence of partial seizures among all patients with epilepsy, but this varies with age. Generalized seizures are more common in early childhood while partial seizures increase in incidence with age such that partial seizures account for 75% of seizures in the elderly [1].


Positron Emission Tomography Temporal Lobe Epilepsy Tuberous Sclerosis Focal Cortical Dysplasia Cortical Development 
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  1. 1.
    So EL (1995) Classifications and epidemiologic considerations of epileptic seizures and epilepsy. Neuroimaging Clin N Am 5(4):513–526PubMedGoogle Scholar
  2. 2.
    Greenberg MK, Barsan WG, Starkman S (1996) Neuroimaging in the emergency room patient presenting with seizure. Neurology 47:26–32PubMedCrossRefGoogle Scholar
  3. 3.
    Maytal J, Krauss JM, Novak G, Nagelberg J, Patel M (2000) The role of brain computed tomography in evaluating children with new onset of seizures in the emergency department. Epilepsia 41(8):950–964PubMedCrossRefGoogle Scholar
  4. 4.
    Shields WD (1993) Neuroimaging in the diagnosis and management of pediatric epilepsy. In: Dodson WE, Pellock JM (eds) Pediatric epilepsy: diagnosis and therapy. Demos, New York, pp 99–106Google Scholar
  5. 5.
    Spencer SS (1994) The relative contributions of MRI, SPECT, and PET imaging in epilepsy. Epilepsia 35[Suppl 6]:S72–S89PubMedCrossRefGoogle Scholar
  6. 6.
    Jack CR Jr (1993) Epilepsy: surgery and imaging. Radiology 189:635–646PubMedGoogle Scholar
  7. 7.
    Britton JW, Cascino GD, Sharbrough FW et al (1994) Lowgrade glial neoplasms and intractable partial epilepsy: efficacy of surgical treatment. Epilepsia 35:1130–1135PubMedCrossRefGoogle Scholar
  8. 8.
    Spetzler RF, Martin DDA (1986) A proposed scheme for grading intracranial arteriovenous malformations. J Neurosurg 65:476–483PubMedCrossRefGoogle Scholar
  9. 9.
    Raymond AA, Fish DR, Sisodiya SM et al (1995) Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy: clinical, EEG and neuroimaging features in 100 adult patients. Brain 118:101–131CrossRefGoogle Scholar
  10. 10.
    Dobyns WB, Truwitt CL (1995) Lissencephaly and other malformations of cortical development: 1995 update. Neuropediatrics 26:132–147PubMedCrossRefGoogle Scholar
  11. 11.
    Barkovich AJ, Kuzniecky RI, Dobyns WB et al (1996) A classification scheme for malformations of cortical development. Neuropediatrics 27:59–63PubMedCrossRefGoogle Scholar
  12. 12.
    Barkovich AJ, Kuzniecky RI, Jackson GD et al (2001) Classification system for malformations of cortical development: update 2001. Neurology 57(12):2168–2178PubMedCrossRefGoogle Scholar
  13. 13.
    Benedikt RA, Brown DC, Walker R et al (1993) Sturge-Weber Syndrome: cranial MR imaging with Gd-DTPA. AJNR Am J Neuroradiol 14:409–415PubMedGoogle Scholar
  14. 14.
    Griffiths PD, Coley SC, Romanaowski CA et al (2003) Contrast-enhanced fluid-attenuated inversion recovery imaging for leptomeningeal disease in children. Am J Neuroradiol 24:719–723PubMedGoogle Scholar
  15. 15.
    Braffman BH, Bilaniuk LT, Naidich TP et al (1992) MR imaging of tuberous sclerosis: pathogenesis of this phakomatosis, use of gadopentetate dimeglumine, and literature review. Radiology 183:227–238PubMedGoogle Scholar
  16. 16.
    Baron Y, Barkovich AJ (1999) MR imaging of tuberous sclerosis in neonates and young infants. AJNR Am J Neuroradiol 20:907–916PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • P. Ruggieri
    • 1
  • A. Nusbaum
    • 2
  1. 1.Section of MRICleveland Clinic FoundationClevelandUSA
  2. 2.Department of RadiologyNew York University Medical SchoolNew YorkUSA

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