The Relevance of Normal-Appearing White Matter Pathology in Multiple Sclerosis
Although the current dogma is that multiple sclerosis (MS) is a T-cell-mediated inflammatory demyelinating disease, a number of studies have provided evidence to challenge this concept. Data obtained through the use of MR techniques such as magnetic resonance spectroscopy (MRS) and magnetization transfer imaging support the argument that MS could be primarily a degenerative disease in which focal inflammatory lesions occur secondarily. This chapter will focus on some of the evidence that supports this concept.
KeywordsMultiple Sclerosis Multiple Sclerosis Patient Magnetic Resonance Spectroscopy Expand Disability Status Scale Magnetization Transfer
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