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MR Spectroscopy of the Normal-Appearing Grey Matter

  • O. Gonen
  • M. Inglese
  • R. I. Grossman
Chapter
Part of the Topics in Neuroscience book series (TOPNEURO)

Abstract

Multiple sclerosis (MS) has been regarded for over a hundred years as an inflammatory demyelinating disease affecting the white matter (WM) of the central nervous system (CNS) [1]. Only over the past decade has this perception been expanded to accommodate the mounting pathological and MRI evidence of axonal injury in the WM lesions of the brain and cord [2–5]. This damage has been shown to extend well beyond the macroscopic lesions into the so-called normal-appearing WM (NAWM) with varying degrees of severity and extent [6–11].

Keywords

Multiple Sclerosis Expand Disability Status Scale Multiple Sclerosis Lesion Magnetization Transfer Ratio Expand Disability Status Scale Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2004

Authors and Affiliations

  • O. Gonen
  • M. Inglese
  • R. I. Grossman

There are no affiliations available

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