Development of the Cerebrospinal Fluid Pathways During Embryonic and Fetal Life in Humans

  • Martin Catala


Trying to understand the mechanisms involved in human development is both a complex and fascinating problem. It is also the absolute prerequisite for an analysis of human malformations. Self-evidently, the genesis of malformation syndromes cannot be understood without a knowledge of the normal steps of development. This contradicts the classical works of human embryology, which were devoted to the analysis of malformation syndromes in the attempt to decipher the normal steps of human development — a method that may be called “reverse embryology”. Nowadays, this old method is of no value and it has been necessary to develop new paradigms to discover the normal pathways of development.


Chick Embryo Vasoactive Intestinal Peptide Choroid Plexus Fetal Life Neural Plate 
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Copyright information

© Springer-Verlag Italia 2005

Authors and Affiliations

  • Martin Catala
    • 1
  1. 1.Laboratoire d’Histologie et Embryologie / UMR CNRS 7000, Faculté de Médecine Pitié-SalpêtrièreUniversité Paris 6ParisFrance

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