Myocardial Preservation during Cardiopulmonary Resuscitation

  • T. Pellis
  • W. Tang
Conference paper


Sudden cardiac death accounts for 300,000 to 400,000 deaths annually in the United States, it is the most common and often first manifestation of coronary heart disease and is responsible for approximately 50% of mortality for cardiovascular diseases in the United States and other developed countries [1, 2]. Sudden cardiac death describes the unexpected natural death from a cardiac cause within a short period, generally ≤ 1 hour from onset of symptoms, in a person without any prior condition that would appear fatal [1]. Cardiopulmonary resuscitation (CPR) effectively restores haemodynamic stability and return to spontaneous circulation (ROSC) in 40% to 60% of arrests. Prolonged survival is significantly lower because of an underlying illness and postresuscitation syndrome, specifically central nervous system injury and left ventricular stunning after resuscitation [3].


Cardiopulmonary Resuscitation KATP Channel Ischemic Precondition Myocardial Stunning Ischaemic Precondition 
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Copyright information

© Springer-Verlag Italia 2002

Authors and Affiliations

  • T. Pellis
    • 1
  • W. Tang
    • 2
  1. 1.Department of Clinical Sciences, Section of Anaesthesia, Intensive Care and Pain ClinicThe Institute of Critical Care MedicinePalm SpringsUSA
  2. 2.The University of Southern CaliforniaKeck School of MedicineLos AngelesUSA

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